Oral disintegrating tablet using roxithromycin and ambroxol hydrochloride as active component and its preparing method and use

Abstract

The invention relates to an orally disintegrating tablet comprising roxithromycin id and ambroxol hydrochloride as active ingredients and its preparation method and uses. Said invention is a medical compound resulting from mixing roxithromycin id and ambroxol hydrochloride as active ingredients and auxiliary material acceptable by pharmacology and for treatment of infection of the upper respiratory tract. Said invention provides means for covering bitter from roxithromycin id and ambroxol hydrochloride and preparation method for orally disintegrating tablets of said medical compound.

Description

technical field

[0001] The invention relates to an orally disintegrating tablet with roxithromycin and ambroxol hydrochloride as active components, a preparation method and application thereof, and belongs to the technical field of medicine. Background technique

[0002] Roxithromycin is a new generation of macrolide antibiotics, mainly acting on Gram-positive bacteria, anaerobic bacteria, chlamydia and mycoplasma. Its in vitro antibacterial effect is similar to that of erythromycin, and its activity against streptococcus, Haemophilus ducrei, Chlamydia trachomatis, Mycoplasma pneumoniae, oral or vaginal anaerobic bacteria is similar to that of erythromycin; The effect of Haemobacter is not as good as that of erythromycins; it also has inhibitory effect on Mycobacterium tuberculosis, most atypical mycobacteria, Campylobacter jejuni, diphtheria bacilli, and Pasteurella multocida; it has no antibacterial activity on G bacteria. Some bacteria have cross-resistance to erythromyc...