Method for preparing pig or cattle's bladder membrane type biological dressing used for treatment of burns

A technology of biological dressings and bladder membranes, applied in the fields of medical science, bandages, absorbent pads, etc., can solve the problems of increasing patient burden, numerous procedures, complicated processing and preparation processes, etc., and achieve the effect of reducing medical expenses and low production costs.

Inactive Publication Date: 2007-04-11
HEBEI IRON AND STEEL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The processing and preparation process of pigskin dressings is complex, with various procedures, and special equipment such as pigskin skinning machines are required, which makes the medical expenses of using pigskin dressings high and greatly increases the burden on patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] After the slaughter of healthy adult pigs, remove the bladder completely, empty the residual urine, use a 10ml syringe to inject 5ml of Liby detergent to remove odors and oily substances, and then rinse the inner cavity of the bladder with about 500ml of water, empty the washing liquid, and perform preliminary cleaning Finally, the fat on the outer layer of the bladder was trimmed, and an air pump was used to inflate the urethral orifice of the bladder to 300kpa to make it expand slowly and fully. After expansion, the volume of the adult pig bladder was about 1800ml. Then cut it longitudinally along the urethral opening to the top of the bladder, make it into a film sheet, put it in 10% povidone iodine solution for disinfection for 30 minutes, wash it with sterile saline, soak it in the skin storage solution for 30 minutes, and perform aseptic operation Put it in a sterile plastic bag under certain conditions, and put it in a refrigerator at 4°C for later use.

Embodiment 2

[0021] The bladder membrane sterilized by 10% povidone iodine in Example 1 was rinsed with sterile saline, soaked in the skin storage solution for 30 minutes, and then placed in a -84°C low-temperature refrigerator for storage. The formula of the skin storage solution is: 4°C physiological saline containing 400,000 units / 500ml of penicillin, and the ratio of bladder membrane area to liquid is 2cm 2 / ml.

[0022] A case of superficial II° burn wound on the left upper arm of a burn patient, the wound area was 2%, the wound was treated with conventional disinfection, the bladder membrane prepared in Example 1 was taken out, fully stretched, the inner surface of the bladder membrane faced the wound, and the wound was spread flat and sterile dressing Bandage. 48 hours after bandaging, the outer dressing was removed, and the bladder membrane was well adhered to the wound. Continue exposure, and dry it with a hair dryer. After 8 days, the wound healed and the bladder membrane fell o...

Embodiment 3

[0024] The present embodiment treats the preparation method of bovine bladder biological dressing for burns, and its steps are:

[0025] A. Bladder extraction: after slaughtering a healthy cow, extract the complete bladder of the cow and empty the residual urine;

[0026] B. Cleaning: Inject cleaning agent into the cow bladder through the urethral opening and rub it to remove peculiar smell and oily substances in the bladder, and then rinse with water and empty the cleaning solution;

[0027] C. Arranging and inflating: Trim the fat on the outer layer of the bladder, inject air into the cow’s bladder through the urethral orifice, and make it expand slowly and fully until the inflation pressure is 350Kpa;

[0028] D. Sectioning: sectioning the expanded bovine bladder longitudinally along the urethral opening to make it into a membrane sheet;

[0029] E. Disinfection: put the dissected cow bladder into 10% iodophor solution by weight for 15 minutes, and then rinse it with steri...

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Abstract

A preparation method of pig or cow bladders membrane biological dressing used in treatment of burns. It relates to a preparation method of pig or cow bladders as a biological dressing in order to provide new biological dressing product and belongs to preparation of medical technology field. The preparation steps are: extract bladder, clean, sort, and aerate, cut, disinfect, and chill. The pig or cow bladder membrane biological dressings prepared by this way can meet the operating requirements of burns in the meanwhile the products are low-cost owing to its no requirement for special equipments in preparation process. Contrast to pigskin dressing, the pig or cow bladder membrane biological dressings are relative good and inexpensive. As preparation method comes out, use pig or cow bladder as the biological dressing in burn treatment can be carried out, the medical costs for burned patients also reduced significantly and a better curative treatment superior to pigskin treatment can be achieved and it has made contributions to the development and technology progress to the burn treatment.

Description

technical field [0001] The invention relates to a preparation method of a biological dressing for treating burns and scalds, in particular to a preparation method using a pig or bovine bladder as a biological dressing, and belongs to the technical field of medical biological dressing preparation. Background technique [0002] At present, among the biological dressings used in the treatment of burns and scalds in the field of burn medicine, pigskin dressings are mostly used, such as irradiated pigskin and glutaraldehyde pigskin. The processing and preparation process of pigskin dressing is complex, with various procedures, and requires special equipment such as pigskin tanning machine, which makes the medical expenses of adopting pigskin dressing remain high and greatly increases the burden on patients. Porcine or bovine bladder has a wide range of sources, low price, soft and elastic texture, can relieve wound pain, reduce exudation, has the characteristics of protecting wou...

Claims

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Application Information

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IPC IPC(8): A61L15/16A61L15/40
Inventor 卢长虹李连贵任红英张瑞梅徐和平张杰王根发刘玉森吴沛东吕淑珍胡太平张德磊
Owner HEBEI IRON AND STEEL
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