Method for treating neurodegeneration

a neurodegeneration and neurodegeneration technology, applied in the field of neurodegeneration treatment, can solve the problems of psychoiatric symptoms and cognitive impairment, negatively affecting both the patient and the caregiver, and achieve the effect of improving the quality of life and reducing the risk of neurodegeneration
US20020055534A1Inactive Publication Date: 2002-05-09HAMILTON PHARMA INC
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Patent Information

Authority / Receiving Office
US ยท United States
Patent Type
Applications(United States)
Current Assignee / Owner
HAMILTON PHARMA INC
Publication Date
2002-05-09
Estimated Expiration
Not applicable ยท inactive patent

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Abstract

There is described a method for treating neurodegeneration, particularly after a stroke, in a mammal, by administration of nefiracetam. This method of treatment allows an improvement in the recovery from stroke.
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Description

[0001] This is a continuation-in-part of application Ser. No. 09 / 511,952, filed on Feb. 23, 2000.

[0002] The present invention concerns the use of a cyclic gamma-aminobutyric acid (GABA) derivative, namely N-(2,6-dimethylphenyl)--2-(2-oxo-1-pyrrolidinyl) acetamide, as a drug for combating neurodegeneration, particularly after a stroke, for improving the Activities of Daily Living (ADL) after a stroke or for recovering, or at least for improving the recovery of, a post-stroke patient.

[0003] It is known that a way to assess physical impairment in post-stroke patients, besides the neurological motor and sensory examination, is to quantitate deficits in the performance of daily activity (ADL) according to assessment scales, such as the John Hopkins Functioning Inventory (JHFI) or analogous ones, which determine the patients' ability to accomplish normal operations, in particular keeping the sitting or standing position, walking, washing, dressing, undressing, eating meals, bathing and us...

Claims

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