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Arrays with elongated features

a technology of arrays and features, applied in the field of arrays, can solve the problems of time-consuming and costly manufacturing of arrays, large quantity of dna available for arrays, and low dna availability, so as to increase the speed of array fabrication, increase the speed of drop deposition head movement relative to the surface, and facilitate identification

Inactive Publication Date: 2006-02-09
BASS JAY K
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This approach reduces the cost and time of array fabrication while facilitating feature extraction by allowing for the production of arrays with a high percentage of elongated features, oriented in a common direction, which can be easily identified, thereby improving the efficiency of the biopolymer array manufacturing process.

Problems solved by technology

In array fabrication, the quantities of DNA available for the array are usually very small and expensive.
This then leads to arrays which are time consuming and costly to manufacture.

Method used

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  • Arrays with elongated features
  • Arrays with elongated features
  • Arrays with elongated features

Examples

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Embodiment Construction

[0031] In the present application, unless a contrary intention appears, the following terms refer to the indicated characteristics. A “biopolymer” is a polymer of one or more types of repeating units. Biopolymers are typically found in biological systems and particularly include polysaccharides (such as carbohydrates), and peptides (which term is used to include polypeptides and proteins) and polynucleotides as well as their analogs such as those compounds composed of or containing amino acid analogs or non-amino acid groups, or nucleotide analogs or non-nucleotide groups. This includes polynucleotides in which the conventional backbone has been replaced with a non-naturally occurring or synthetic backbone, and nucleic acids (or synthetic or naturally occurring analogs) in which one or more of the conventional bases has been replaced with a group (natural or synthetic) capable of participating in Watson-Crick type hydrogen bonding interactions. Polynucleotides include single or mult...

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Abstract

Arrays having multiple biopolymer features on a substrate, including elongated features which have a length / width ratio greater than 1.3 or more. Such arrays may be oriented in various directions and of shapes described, and fabricated using apparatus, methods, or computer program products of the invention.

Description

RELATED APPLICATION [0001] This application claims priority to, and is a divisional of, copending application Ser. No. 10 / 135,944, filed Apr. 29, 2002, under 35 U.S.C. §120, the entirety of which is incorporated herein by reference.FIELD OF THE INVENTION [0002] This invention relates to arrays, particularly biopolymer arrays such as DNA or protein arrays, which are useful in diagnostic, screening, gene expression analysis, and other applications. BACKGROUND OF THE INVENTION [0003] In the following discussion and throughout the present application, no cited reference is admitted to be prior art to the present application. [0004] Biopolymer arrays, such as polynucleotide arrays and peptide array, are known and may be used, for example, as diagnostic or screening tools. Such arrays include regions (sometimes referenced as spots or features) of usually different sequence polynucleotides or peptides arranged in a predetermined configuration on a substrate. The array is “addressable” in t...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): G01N1/28C12M1/34B01J19/00B01L3/02B29C31/04B29C41/20B29C41/36B41J2/21B41J3/407C40B40/06C40B60/14C40B70/00
CPCB01J19/0046C40B70/00B01J2219/00529B01J2219/00554B01J2219/00596B01J2219/00608B01J2219/00677B01J2219/00722B01L3/0241B29C31/045B29C41/20B29C41/36B41J2/2114B41J3/407B82Y30/00C40B40/06C40B60/14B01J2219/00378
Inventor BASS, JAY K.
Owner BASS JAY K