Use of a container of an inorganic additive containing plastic material

Inactive Publication Date: 2006-06-29
UDO MATTERN
View PDF11 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0010] This object is achieved by an use of a container, made of an additive containing plastic material, for reducing physical / chemical interaction between the container and an oil, fat and / or wax containing formulation contained therein.
[0023] Surprisingly, it was found that a container of an inorganic additive containing plastic material may be advantageously utilized for keeping oil, fat and / wax containing formulations, for example oily formulations of steroid hormones, in that the use of such a container will reduce physical-chemical interactions of the container and the formulation, especially the adsorption of the formulation to the plastic material.
[0024] Surprisingly, the inventor has found that TiO2 can also be used for a purpose for which it was not intended to be used so far: By adding it to plastic packaging material the physical-chemical interaction of certain oily formulations with the container, restricting its use, can be prevented.

Problems solved by technology

However it is known that, due to their character, there are some limitations.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0026] In nasal application forms the suitability of the device for administration is of major importance. This applies to improving patient's compliance by convenient administration. But this also applies to pharmaceutical necessities such as the uniformity of emitted dose and the compatibility of the formulation with the primary packaging material. In pharmaceutical applications it is essential to use inert material for primary packaging; the galenical formulation, the active ingredient and the excipients, should not adversely be influenced by any interaction.

[0027] In principle there are two materials and two types for packaging of nasal formulations: glass vs. plastic and multiple-dose vs. unit-dose containers. The main advantages of plastic materials are their flexibility allowing for a wide range of designs, low weight, shatter resistance, and easy handling. Especially suitable for nasal application are unit-dose containers from plastic because of their small size, because no...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The present invention relates to the use of a container, made of an inorganic additive containing plastic material, for reducing physical / chemical interaction between the container and an oil, fat and / or wax containing formulation contained therein.

Description

FIELD OF THE INVENTION [0001] The present invention relates to the use of a container of an inorganic additive containing plastic material. DESCRIPTION OF THE RELELATED ART [0002] Plastic containers are readily used for pharmaceutical preparations. However it is known that, due to their character, there are some limitations. Thus to suppress the reactivity of containers from polyethylene or polypropylene and their copolymers / blends towards certain chemicals several methods are used: plasticizers are avoided which would increase the motility of the chain molecules, polymers of higher density or polyolefin blends (e.g. polypropylene / polyacrylate) are used, the wall thickness is increased or the containers are wrapped (e.g. aluminium foil) or sealed (e.g. fluorination, silicone). [0003] U.S. Pat. No. 4,123,417 (Finberg, 1978) claims that the toughness of LDPE can be increased by a blend comprising low density polyethylene containing an amorphous ethylene-propylene copolymer having a ce...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): B01L9/00
CPCA61J1/14B65D1/0207A61P5/26
Inventor MATTERN, CLAUDIA
Owner UDO MATTERN
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap