Composition for external preparation for skin

a technology of external preparation and composition, which is applied in the direction of peptide/protein ingredients, extracellular fluid disorder, immunological disorders, etc., can solve the problems of repeated inappropriate external application, rebound phenomenon induced by discontinuation of external application, and difficult application to areas of high drug absorbability such as the face, and achieves the effects of improving erythema, papules and scales, and little inflammatory
US20120208756A1Inactive Publication Date: 2012-08-16IGISU
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Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
IGISU
Publication Date
2012-08-16
Estimated Expiration
Not applicable · inactive patent

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Abstract

The problem to be solved by the present invention is to provide a safe and efficacious therapeutic agent for dermatitis which is not only safe and efficacious for patients with dermatitis, in particular atopic dermatitis, but also significantly effective for severe cases that are judged to be intractable by conventional external preparations, and which is also safely applicable to affected areas such as the face and neck, as well as to subjects with sensitive skin, such as infants and females. Furthermore, the invention aims to provide an external preparation that is efficacious as skin care cosmetics having effects to improve elasticity and wrinkles of the skin, moisturizing effects, and hair-growth effects.The means for solving the problem is a skin external-preparation composition, in particular, a therapeutic agent for dermatitis or a skin texture-improving agent, having C-type natriuretic peptide (CNP) or B-type natriuretic peptide (BNP) as the active ingredient.
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Description

FIELD OF INVENTION

[0001] The present invention relates to a skin external-preparation composition comprising C-type natriuretic peptide (CNP) or B-type natriuretic peptide (BNP) as its active ingredient. In particular, the present invention relates to a therapeutic agent for skin disease or a skin texture-improving agent comprising C-type natriuretic peptide (CNP) or B-type natriuretic peptide (BNP) as its active ingredient.BACKGROUND ART1. Dermatitis:

[0002] Dermatitis is an inflammatory reaction of the skin, and is the most prevalent skin disease. Often in acute skin inflammations, clinically, edematous erythema is presented initially, followed by erythematous lesions with papules and serous papules, then formation of vesicles, pustules, erosions, crusts and scales, followed by healing process. When a skin inflammation becomes chronic, thickened skin, lichenification and pigmentations are observed, and they are often associated with itching.

[0003] Dermatitis includes contact dermatiti...

Claims

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