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204 results about "Skin striae" patented technology

"Striae" is also a general term referring to thin, narrow grooves or channels, or a thin line or band especially if several of them are parallel or close together. Stretch marks, also known as striae, are a form of scarring on the skin with an off-color hue.

Peptides, compositions comprising them and uses in particular cosmetic uses

ActiveUS20170157014A1Improve appearance and general statePrevention of signCosmetic preparationsPeptide/protein ingredientsCell-Extracellular MatrixCollagen i
The peptides have the general following formula: X-Pro*-Pro*-Xaa-Y in which: —Xaa is selected from Leucine (Leu, L), Arginine (Arg, R), Lysine (Lys, K), Alanine (Ala, A), Serine (Ser, S), and Aspartic acid (Asp, D); —At the N terminal end of the peptide, X is selected from H, —CO—R1 and —SO2—R1; —At the C terminal end of the peptide, Y is selected from OH, OR1, NH2, NHR1 and NR1R2; —R1 and R2 are, independently from each other, selected from an alkyle, aryle, aralkyle, alkylaryl, alkoxy and aryloxy group, that can be linear, branched, cyclic, poly-cyclic, non-saturated, hydroxylated, carbonylated, phosphorylated and / or sulfured, and which skeletum can comprise an heteroatom, in particular an O, S and / or N atom;—Pro* correspond to a Proline, an analogue or derivative thereof; —if X is H then Y is selected from OR1, NH2, NHR1 and NR1R2, and if Y is OH then X is —CO— or —SO2—R1; and the peptide hypoxanthine-Pro-Pro-Arg being excluded. The invention provides the use of the peptides of above formula I to stimulate the synthesis of the molecules constituting the dermal extracellular matrix, including collagen I and IV and elastin. A cosmetic treatment according to the invention includes anti-aging, anti-wrinkles, improving mechanical properties of the skin, firmness / tone / elasticity / suppleness / flexibility, increasing density and volume of the skin, restructuring effect, fighting stretch marks, improving skin barrier and / or skin hydration.
Owner:SEDERMA SA
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