Neuromodulation using modulated pulse train

Abstract

A neuromodulation system comprises a plurality of electrical terminals configured for being respectively coupled to a plurality of electrodes, a user interface configured for receiving input from a user that selects one of a plurality of different shapes of a modulating signal and / or selects one of a plurality of different electrical pulse parameters of an electrical pulse train, neuromodulation output circuitry configured for outputting an electrical pulse train to the plurality of electrical terminals, and pulse train modulation circuitry configured for modulating the electrical pulse train in accordance with the selected shape of the modulating signal and / or selected electrical pulse parameter of the electrical pulse train.

Description

RELATED APPLICATION DATA[0001]The present application claims the benefit under 35 U.S.C. §119 to U.S. provisional patent application Ser. No. 61 / 774,835, filed Mar. 8, 2013. The foregoing application is hereby incorporated by reference into the present application in its entirety.FIELD OF THE INVENTION[0002]The present invention relates to neuromodulation systems, and more particularly, to neuromodulation system utilizing electrical pulse trains.BACKGROUND OF THE INVENTION[0003]Implantable neuromodulation systems have proven therapeutic in a wide variety of diseases and disorders. Pacemakers and Implantable Cardiac Defibrillators (ICDs) have proven highly effective in the treatment of a number of cardiac conditions (e.g., arrhythmias). Spinal Cord Stimulation (SCS) systems have long been accepted as a therapeutic modality for the treatment of chronic pain syndromes, and the application of tissue stimulation has begun to expand to additional applications such as angina pectoralis and...

AI Technical Summary

Benefits of technology

The present invention is related to a neuromodulation system that can adjust the pulse train of an electrical signal to modulate the activity of nerves. The system includes a plurality of electrical terminals, a user interface, and a pulse train modulation circuitry. The user interface allows the user to define the shape of the modulating signal, which the system then uses to generate an electrical pulse train. The pulse train modulation circuitry can adjust various parameters of the pulse train, such as pulse amplitude, pulse rate, and pulse duration, to achieve the desired effect on nerve activity. The system can be housed in a casing for easy use and protection. The technical effects of the invention include improved precision and control over nerve modulation, as well as improved safety and reliability.

Problems solved by technology

However, neuron response is a dynamic time course that can vary with the sequential stimulation, thereby limiting the volume of neural tissue that may be consistently stimulated.

Furthermore, it is known that neural tissue may accommodate, adapt, and / or habituate to a continuous tonic input, resulting in a diminished neural response over time.

One disadvantage of high-frequency pulsed electrical energy is that it consumes an excessive amount of energy, thereby requiring the neuromodulator device to be charged more often.

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