Container with low particulate emission and friction controlled dry sliding surface and methods for producing same

Abstract

A container is provided that includes a container body with an outer surface and an inner surface. The inner surface contains silicon oxide and the silicon oxide containing inner surface is at least partially modified with a fluorine containing compound. The fluorine containing compound is chemically bonded to the silicon oxide of the container body via at least one Si—O—Si bond.

Description

CROSS REFERENCE TO RELATED APPLICATIONS[0001]This application is a continuation of U.S. application Ser. No. 14 / 250,494 filed Apr. 11, 2014, which claims the benefit of U.S. Provisional Application 61 / 847,584 filed Jul. 18, 2013 and claims benefit under 35 USC § 119(a) of German Application 10 2013 103 676.7 filed Apr. 11, 2013, the entire contents of each of which are incorporated herein by reference.BACKGROUND1. Field of the Invention[0002]The invention generally relates to containers and more particularly to containers that are part of a pharmaceutical packaging or of a medical device or a sterile packaging, such as syringe, cartridge or cannula systems and pharmaceutical vials.2. Description of Related Art[0003]In pharmaceutical packaging, such as syringe, cartridge or cannula systems and pharmaceutical vials, high demands are placed on the friction properties of the inner surface of the packaging. For example, the syringe plunger or the stopper of a vial should slide over the i...

AI Technical Summary

Benefits of technology

The invention provides a container that reduces particulate emission from the inner surface of the container into the contents. The container also exhibits improved friction properties and can be manufactured cost-efficiently and with low complexity. Additionally, the container can dispense with additional lubricating oils such as silicone oils.

Problems solved by technology

That means, the desired sliding properties are only achieved by a very complex process using multi-stage process steps.

Furthermore, what is suggested is not an oil-free solution, rather the silicone oil is merely replaced by another lubricating oil.

Even after plasma curing, this perfluoropolyether-based lubricating oil includes free lubricating oil which can migrate into the drug solution, where it can lead to unwanted side effects.

However, a drawback thereof is that silicone oil molecules might migrate from the surface into the active substance solution stored in the packaging.

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