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Use of pydiflumetofen for the reduction of mycotoxin contamination in plants

a technology of mycotoxin contamination and pydiflumetofen, which is applied in the field of plant mycotoxin contamination reduction, can solve the problems of crop contamination by fungal toxins, insufficient wounding, and serious pests of economically important agricultural crops

Pending Publication Date: 2021-02-04
BAYER CROPSCIENCE AG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

Pydiflumetofen effectively reduces mycotoxin levels by up to 80% in plants and plant materials, including cereals like wheat, before and after harvest, and during storage, providing a comprehensive solution to mycotoxin contamination.

Problems solved by technology

Numerous fungi are serious pests of economically important agricultural crops.
Further, crop contamination by fungal toxins is a major problem for agriculture throughout the world.
Mycotoxins, such as aflatoxins, ochratoxins, patulin, fumonisins, zearalenones, and trichothecenes, are toxic fungal metabolites, often found in agricultural products that are characterized by their ability to cause health problems for humans and vertebrates.
Further, mycotoxin-producing Fusarium species are destructive pathogens and attack a wide range of plant species.
Therefore prohibiting fungal infection via controlling insects that promote infection by wounding is not sufficient for reducing effectively mycotoxin contamination of maize, especially for DON, Zearalenone and aflatoxins.
It has also to be mentioned that breeding for fungal resistance in crops in contrast to insecticidal resistance is much more difficult.
There have been several classical and transgenic breeding approaches. but obviously a high level of resistance is difficult to obtain.

Method used

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  • Use of pydiflumetofen for the reduction of mycotoxin contamination in plants
  • Use of pydiflumetofen for the reduction of mycotoxin contamination in plants
  • Use of pydiflumetofen for the reduction of mycotoxin contamination in plants

Examples

Experimental program
Comparison scheme
Effect test

example a

Application of Pydiflumetofen on the Deoxynivalenol Content of Wheat

[0175]The field trial in winter wheat was conducted in Germany in spring / summer 2015.

[0176]Seeds of the winter wheat variety “Reaper” were planted in autumn 2014. Fertilization, herbicide- and plant growth regulator applications were carried out according to the local agricultural practice.

[0177]The trial was conducted with 3 fully randomized replicates. The plot size was 15 m2.

[0178]The compound Pydiflumetofen was sprayed on Jun. 10, 2015, at BBCH—growth stage 65 with an use rate of 75 g a.i. / ha. Pydiflumetofen was applied as a 100 EC formulation adding an adjuvant. In the late evening of the same day, an inoculation with spores of Gibberella zeae was carried out by spray application.

[0179]After harvest, the Deoxynivalenol content of the wheat kernels was analyzed by HPLC-MS / MS.

[0180]The effect of Pydiflumetofen on the Deoxynivalenol content is shown in table 1.

TABLE 1Impact of Pydiflumetofen on the Deoxynivalenolc...

example b

on of Pydiflumetofen on the Deoxynivalenol Content of Wheat

[0181]Six field trials of wheat analysing Mycotoxin contamination were performed at locations in France and Germany during the season of 2016 with seed planting in spring. Pydiflumetofen was applied to wheat plants as a 100 EC formulation at a rate of 45 to 60 grams / ha. Mycotoxins were measured 67 days after application of Pydiflumetofen on 2016 Aug. 8.

[0182]Results for mycotoxin content are shown in table 2, result for severity of Fusarium infection are shown in table 3.

[0183]UTC: Untreated control

[0184]DON: deoxynivalenol

[0185]ZEA: zearalenone

TABLE 23-AcetylRateDONZEADeoxynivalenolNivalenolProduct(s)Country(g a.i. / ha)(ppb)(ppb)(ppb)(ppb)UTCFrance0188525not testednot testedPydiflumetofenFrance45789not testednot testedPydiflumetofenFrance6092011not testednot testedUTCFrance03916 0189not testedPydiflumetofenFrance45117063not testedPydiflumetofenFrance601068not testedUTCGermany06694not testednottested126PydiflumetofenGermany45...

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Abstract

The present invention relates to the novel use of the pyrazole carboxylic acid amide derivative Pydiflumetofen, compositions comprising this compound and its use in methods for the reduction of mycotoxin contamination in plants. Pydiflumetofen is also useful in increasing yield, in particular in cereals eg. wheat.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This application is a Continuation of U.S. patent application Ser. No. 15 / 766,726, filed 6 Apr. 2018, which is a National Stage entry of International Application No. PCT / EP2016 / 074109, filed 7 Oct. 2016, which claims priority to European Patent Application No 15189239.5, filed 9 Oct. 2015. Each of these applications is incorporated by reference in its entiretyFIELD OF THE INVENTION[0002]The present invention relates to the novel use of the pyrazole carboxylic acid amide derivative Pydiflumetofen, compositions comprising this compound and its use in methods for the reduction of mycotoxin contamination in plants. Pydiflumetofen is also useful in increasing yield, in particular in cereals eg. wheat.BACKGROUND OF THE INVENTION[0003]Numerous fungi are serious pests of economically important agricultural crops. Further, crop contamination by fungal toxins is a major problem for agriculture throughout the world.[0004]Mycotoxins, such as aflatox...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A01N43/56C07D233/56
CPCA01N43/56A01C1/06C07D233/56A01N25/00
Inventor DAHMEN, PETERCOQUERON, PIERRE-YVESWETCHOLOWSKY, INGO
Owner BAYER CROPSCIENCE AG