11 results about "Anesthesia analgesia" patented technology

The invention provides an intraoperative nursing anesthesia analgesia effect evaluation method and system based on data analysis. The method comprises the following steps: acquiring anesthesia information, adverse factors and post-anesthesia physiological indexes of a patient, converting the physiological indexes into relative values, distributing weights, and calculating a weighted sum; meanwhile, an adjustment coefficient is calculated according to the total number and existence number of adverse factors. And constructing an analgesic effect comprehensive evaluation model in combination with the weighted sum and the adjustment coefficient. And inputting the physiological indexes and the adverse factors of the patient to the model, calculating an analgesic effect evaluation score, and associating the score with the anesthesia information. According to the method, various factors in the anesthesia analgesia process are comprehensively considered, the physiological state of a patient is reflected, the influence of adverse factors is considered, and a comprehensive and accurate evaluation result is provided.

The invention provides an analgesic microneedle patch based on 3D printing and a preparation method and application thereof, and belongs to the technical field of biomedical materials.The preparation method of the hydrogel microneedle patch based on 3D printing comprises the following steps that 1, cold water fish skin gelatin is dissolved in DPBS, and a gelatin solution is obtained; (2) mixing methacrylic anhydride and gelatin liquid to generate polymerization reaction, so as to obtain a hydrogel material; and 3) loading an anesthetic and analgesic drug on the hydrogel material, and printing by a photocuring 3D printing method to obtain the hydrogel microneedle patch. The 3D printing technology is combined with a microneedle which is a dysmenorrhea-free skin drug delivery system, local anesthetics are loaded into the microneedle patch, on the basis of painless drug delivery, the drug delivery efficiency is improved, the drug onset time is shortened, and then the effect of effectively, rapidly and safely playing a local anesthesia role is achieved.

The postoperative anesthesia analgesia equipment comprises a barrel shell, a gasket is installed at the bottom end of the barrel shell, a plurality of copper strips are installed on the top face of the gasket in the barrel shell, the copper strips extend outwards at equal intervals with the center of the gasket as the circle center, and connecting strips are integrally formed and fixed to the copper strips; a semiconductor chilling plate is fixed on the copper bar in the center of the gasket through an adhesive, a top cover plate is mounted at the top of the barrel shell, a fixed frame is mounted in the middle of the top cover plate, a movable frame sliding along the fixed frame is inserted in the fixed frame, one end of the movable frame abuts against the copper bar, and a fan is mounted in the movable frame. The semiconductor chilling plate is used as a cold and heat source, heat supply or cold supply can be conducted only by supplying power and switching the current supply direction, repeated use can be achieved, meanwhile, the fan is arranged for the semiconductor chilling plate, cold energy or heat energy of the non-use end can be actively blown out, and the service life of the semiconductor chilling plate is prolonged. And heat or cold output and used by the semiconductor chilling plate is conducted through the copper bar, so that a larger range can be covered.

A disposable postoperative local infiltration anesthesia analgesia system comprises an anesthesia catheter, a guide wire, a lacerable trocar, an injector and an infusion pump, the anesthesia catheter can be sleeved with the lacerable trocar in a matched mode, the guide wire can be sleeved with the anesthesia catheter in a matched mode, a plurality of micropores are formed in the side wall of one end of the anesthesia catheter, and the infusion pump is connected with the guide wire. The micropores are evenly distributed in the circumferential direction of the anesthesia catheter, the other end of the anesthesia catheter is connected with a first connector tube and a second connector tube, a connector of an infusion pump can be in butt joint with the first branch connector tube or the second connector tube, and an injector can be in butt joint with the first branch connector tube or the second connector tube. The anesthesia catheter can be placed into a pain part of a patient through the guide wire and the tearable trocar, wound infiltration is continuously carried out through anesthetic, pain can be accurately, directly and intensively relieved, the using amount of the anesthetic is reduced, the anesthetic is small in side effect or free of side effect, and the anesthesia catheter is convenient to use. Various severe side effect risks caused by opioid abuse can be effectively avoided.

The present invention provides an anesthesia mask, belonging to the technical field of medical devices; comprising a mask body, a first airbag fixedly mounted on the top of the mask body, the first airbag being filled with air, a first ventilation tube that penetrates and extends into the mask body being fixedly sleeved on the top of the first airbag, and a detection component, a blocking component, a first limiting component and a second limiting component connected to each other are mounted on the mask body. The present invention can determine whether the anesthesia mask will leak during use by setting a slide, so that the anesthetic dose entering the patient's body is the same as the expected value, avoiding the patient from being awake during the operation, ensuring the anesthesia and analgesia effect on the patient, reducing the patient's psychological pressure, and avoiding the patient from having a stress response, thereby improving the safety of the operation, and making full use of the anesthetic, saving medical costs, and further ensuring the effective anesthesia of the patient, improving the safety of the operation.

The invention relates to an application of a traditional Chinese medicine inunction prescription for nourishing liver and kidney as a medicine for treating polymyalgia rheumatic, and belongs to the field of traditional Chinese medicine preparations for treating polymyalgia rheumatic. In the traditional Chinese medicine inunction prescription, polygonum cuspidatum, kalimeris indica root and ramulus mori are used as monarch drugs for dispelling wind, eliminating dampness and easing joint movement; the pedicularis and the radix angelicae have the effects of dispelling wind and relieving pain, enhancing local blood circulation and promoting drug absorption, the borneol, the gypsum and the nightshade assist the monarch drug to enhance the anti-inflammatory effect, and the discolor cinquefoil herb and the bulbus tulip bulb have the effects of clearing away heat and toxic materials and relieving swelling and pain and are all ministerial drugs; the manyleaf paris rhizome and the artemisia anomala are used for assisting the monarch drugs to dissipate blood stasis, relieve pain and promote blood circulation to subdue swelling, and the pepper, the croton and the far infrared ceramic powder are used for anesthesia, analgesia and enhancement of drug permeability and are used as adjuvant drugs; rhododendron molle and periploca forrestii schltr harmonize the medicines, enhance the overall curative effect and serve as conductant medicines together. Therefore, according to the traditional Chinese medicine inunction prescription provided by the invention, dialectical treatment is performed from the perspective of nourishing the liver and the kidney, and the treatment effect is relatively good.

The invention discloses a temperature-sensitive modified chitosan hydrogel-loaded local anesthetic sustained-release analgesic system, a preparation method and an application. A temperature-sensitive chitosan derivative is dissolved in water at low temperature, a local anesthetic analgesic aqueous solution or a degradable polymer microsphere loaded with a local anesthetic analgesic is added in a liquid state and mixed evenly at low temperature, and the system is injected into a part requiring local anesthesia and analgesia to quickly form a gel at body temperature and release the drug slowly. The main features of the local anesthetic sustained-release analgesic composite hydrogel system are simple preparation, no organic solvent is used, and the local anesthetic analgesic can be slowly released, which solves the problem of the existing local anesthetics such as bupivacaine hydrochloride, ropivacaine and lidocaine being released too quickly and having a short action time; it can completely fill irregular wounds, has good biocompatibility and biodegradability, and is conducive to long-term local anesthesia, analgesia, anti-inflammatory and antipruritic effects and promotes wound healing.

The invention provides a microneedle anesthesia analgesia system and method for painless local anesthesia injection, and the system comprises a bionic gradient microneedle array, a mechanical drive module, an electromagnetic lead-in module, a multi-mode biosensor and a PID controller. The bionic gradient microneedle array is connected with the mechanical driving module and the electromagnetic leading-in module; the electromagnetic lead-in module is used for promoting the diffusion of the anesthetic in the in-vivo tissue; the multi-mode biosensor is used for monitoring the concentration of anesthetic in vivo, the pH value of tissues and drug metabolites in real time and sending the acquired information to the PID controller; and the PID controller is used for dynamically adjusting the microneedle penetration length, the drug release rate and the electromagnetic introduction intensity parameter according to the information sent by the multi-mode biosensor. By means of the technical scheme, the local anesthesia analgesic effect without injection pain is truly achieved.

This invention relates to the field of facial expression recognition technology, specifically to an intelligent assessment method for anesthesia and analgesia status based on facial expression recognition. The method includes: for the user to be assessed, obtaining a mask overall translation reference vector and a facial pixel movement vector matrix; stripping the global translation component from the facial pixel movement vector matrix and generating a local contraction deformation matrix; based on the mask overall translation reference vector, performing linkage component removal processing on the local deformation vectors of each grid node in the local contraction deformation matrix to separate independent contraction components and constructing a facial independent contraction feature matrix; inputting the facial independent contraction feature matrix into a convolutional neural network to extract the classification probabilities of each preset category of facial movements, and performing weighted fusion processing to determine the analgesia status assessment index of the user to be assessed, which indicates that the user only responds to independent facial muscle contractions induced by the patient's central nervous system, effectively improving the accuracy of the anesthesia and analgesia status assessment results.

This invention relates to the fields of biotechnology and pharmacogenomics detection, and discloses a kit and application for gene detection of drugs used in general anesthesia. The kit contains a primer set for detecting genetic polymorphic loci related to commonly used perioperative anesthetic, analgesic, and muscle relaxant drugs. The primer set includes multiplex PCR amplification primers and single-base extension primers. The kit also includes multiplex PCR amplification reaction solution, SAP reaction solution, SAP enzyme, extension buffer, single-base extension termination mixture, extension reaction enzyme, desalting purification resin, standards, calibrators, deionized water, and instructions for use. This invention uses matrix-assisted laser desorption / ionization time-of-flight mass spectrometry (MALDI-TOF) to genotype SNP loci, obtaining genotype results for 103 genetic polymorphic loci in a single test. This allows for the prediction of individual differences in drug metabolism, drug efficacy, and adverse reaction risk, providing a basis for personalized medication in general anesthesia.

The simple medicine injector comprises an upper shell, the lower side of the upper shell is connected with a lower shell, two inserting plates are symmetrically and fixedly arranged on the side wall of the side, close to the lower shell, of the upper shell, and inserting grooves corresponding to the two inserting plates are formed in the lower shell; two inserting grooves are formed in the upper shell, fixing mechanisms corresponding to the inserting plates are arranged in the two inserting grooves, a plurality of arc-shaped pipes are fixedly arranged on the inner wall of the upper shell in the circumferential direction, a plurality of medicine suction pipes are fixedly arranged on the upper shell in the circumferential direction, the medicine suction pipes penetrate through the upper wall of the upper shell, and a medicine suction head is fixedly arranged at the end, away from the upper shell, of each arc-shaped pipe. And a piston plate is arranged in each arc-shaped pipe in a sliding manner. Compared with the prior art, the device can suck various medicines at the same time, the medicines do not need to be sucked for multiple times to be injected into the liquid storage bag, the efficiency is greatly improved, liquid medicine can be fully mixed firstly and then injected, compared with sequential liquid injection, the mixing degree of the medicines is improved, and the using effect of the medicines is guaranteed.