2 results about "Anesthesia analgesia" patented technology

This invention relates to the field of facial expression recognition technology, specifically to an intelligent assessment method for anesthesia and analgesia status based on facial expression recognition. The method includes: for the user to be assessed, obtaining a mask overall translation reference vector and a facial pixel movement vector matrix; stripping the global translation component from the facial pixel movement vector matrix and generating a local contraction deformation matrix; based on the mask overall translation reference vector, performing linkage component removal processing on the local deformation vectors of each grid node in the local contraction deformation matrix to separate independent contraction components and constructing a facial independent contraction feature matrix; inputting the facial independent contraction feature matrix into a convolutional neural network to extract the classification probabilities of each preset category of facial movements, and performing weighted fusion processing to determine the analgesia status assessment index of the user to be assessed, which indicates that the user only responds to independent facial muscle contractions induced by the patient's central nervous system, effectively improving the accuracy of the anesthesia and analgesia status assessment results.

This invention relates to the fields of biotechnology and pharmacogenomics detection, and discloses a kit and application for gene detection of drugs used in general anesthesia. The kit contains a primer set for detecting genetic polymorphic loci related to commonly used perioperative anesthetic, analgesic, and muscle relaxant drugs. The primer set includes multiplex PCR amplification primers and single-base extension primers. The kit also includes multiplex PCR amplification reaction solution, SAP reaction solution, SAP enzyme, extension buffer, single-base extension termination mixture, extension reaction enzyme, desalting purification resin, standards, calibrators, deionized water, and instructions for use. This invention uses matrix-assisted laser desorption / ionization time-of-flight mass spectrometry (MALDI-TOF) to genotype SNP loci, obtaining genotype results for 103 genetic polymorphic loci in a single test. This allows for the prediction of individual differences in drug metabolism, drug efficacy, and adverse reaction risk, providing a basis for personalized medication in general anesthesia.