7 results about "SENILE PLAQUE FORMATION" patented technology

The present application provides a kind of application of the steroid compound in preparation prevention or treatment skin pigmentation related condition or anti-aging related product, the steroid compound is as shown in formula I, and has treatment, lightening and / or alleviating effect on senile plaques, freckles, chloasma and the like caused by pigmentation on the skin of mammal.(I).

The invention provides a high-concentration hydrogen peroxide emulsion for treating senile plaques and application thereof, and in the high-concentration hydrogen peroxide emulsion, hydrogen peroxide is used as an active component, can oxidize and decompose melanin in skin, and has a freckle removing effect; the hydrogenated polydecene is used as an emollient, so that the skin can be moistened and the texture of the skin is improved; hydrogenated castor oil (PEG-40) is used as an emulsifier, so that an emulsion system is stable; the bisabolol has anti-inflammatory and soothing effects, and can relieve the irritation of hydrogen peroxide to the skin; citric acid can adjust the pH value of the emulsion, so that the emulsion is more suitable for the physiological environment of skin; sodium hyaluronate has a moisturizing effect and can enhance the barrier function of skin. All the components have a synergistic effect, so that the emulsion has a good senile plaque treatment effect, and meanwhile, irritation to skin is reduced.

To provide technology that can be used to inhibit aggregation of β-amyloid protein (Aβ) and microtubule-binding protein Tau, which bring about senile plaque (senile plaque: AP) and neurofibrillary tangle (Neurofibrillary Tangle: NFT).SOLUTION: The present invention provides a protein aggregation inhibitor containing mesostructured particles of calcium hydrogen carbonate as an active ingredient.SELECTED DRAWING: Figure 2

The application provides a tissue staining method based on antigen repair treatment combined with silver staining, comprising the following steps: a) high-temperature heat repair of a tissue section to be treated with an antigen repair solution, and washing with water after cooling to obtain a repaired tissue section; b) silver staining of the repaired tissue section obtained in step a), dehydration, and then mounting to obtain a stained tissue section. Compared with the prior art, the tissue staining method based on antigen repair treatment combined with silver staining provided by the application adopts specific process steps and conditions to realize overall good interaction: first, the brain tissue is subjected to antigen repair treatment, and then the silver staining technology is adopted, which significantly improves the signal-to-noise ratio of the senile plaque region, and ideal staining effect is obtained, which can effectively improve the detail visibility in pathological detection, help more accurately evaluate the morphology and distribution characteristics of the senile plaque, and has a wide application prospect.

The invention provides a traditional Chinese medicine composition for resisting Alzheimer's disease as well as a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following active ingredients in parts by weight: 6-50 parts of gastrodia elata, 6-50 parts of uncaria rhynchophylla, 9-60 parts of concha haliotidis, 6-50 parts of prepared rehmannia root, 6-50 parts of radix cyathulae, 3-30 parts of semen raphani, 3-30 parts of eucommia ulmoides, 3-30 parts of parasitic loranthus, 3-30 parts of scutellaria baicalensis, 3-30 parts of herba lycopi, 3-30 parts of vine of multiflower knotweed and 3-30 parts of cinnabar root poria. The raw materials of the medicine are common, the preparation method is simple and easy to operate, the medicine has wide application value, after oral administration of the medicine, cognitive impairment of a transgenic mouse model of the Alzheimer's disease can be obviously improved, deposition of age pigment in brain tissue is reduced, meanwhile, the number of activated microglia and astroglia in the brain tissue is reduced, and the treatment effect of the Alzheimer's disease is improved. The compound inhibits the formation of A beta in brain tissues, and has a new application of anti-Alzheimer's disease drugs.

Provided is a protein aggregation inhibitor containing meso-structured particles of calcium hydrogencarbonate as an active ingredient, as a technology that can be used in order to inhibit the aggregation of β-amyloid protein (Aβ) or microtubule-associated protein Tau which causes a senile plaque (AP) and a neurofibrillary tangle (NFT).

The invention provides a fire needle treatment device for treating senile plaques, and belongs to the technical field of medical instruments. Comprising a mechanical arm, a connecting disc is installed on the wrist (output end) of the mechanical arm, a camera is installed on one side of the connecting disc, an illuminating lamp is arranged outside the connecting disc and located on the outer side of the camera, a connecting arm and a needle applying assembly are fixedly connected to one side of the connecting disc, and the needle applying assembly is used for pressing and fixing the skin at the age pigment. And the needle applying assembly is connected with the connecting arm. The mechanical arm is provided with the needle applying mechanism and the disinfection mechanism to achieve automation of the acupuncture process, the needle applying position and the needle inserting depth can be accurately controlled, the treatment accuracy is greatly improved, a needle instrument can be heated while the skin is pressed, it is ensured that after the skin is fixed, the needle instrument can penetrate into an age pigment area in a seamless connection mode, and the acupuncture effect is improved. The treatment effect on the senile plaque is improved, and the treatment experience of a patient is improved.