The application provides a
tissue staining method based on
antigen repair treatment combined with silver
staining, comprising the following steps: a) high-temperature heat repair of a
tissue section to be treated with an
antigen repair solution, and washing with water after cooling to obtain a repaired
tissue section; b) silver
staining of the repaired
tissue section obtained in step a),
dehydration, and then mounting to obtain a stained tissue section. Compared with the prior art, the
tissue staining method based on
antigen repair treatment combined with silver
staining provided by the application adopts specific process steps and conditions to realize overall good interaction: first, the
brain tissue is subjected to antigen repair treatment, and then the silver staining technology is adopted, which significantly improves the
signal-to-
noise ratio of the senile plaque region, and ideal staining effect is obtained, which can effectively improve the detail
visibility in
pathological detection, help more accurately evaluate the morphology and distribution characteristics of the senile plaque, and has a wide application prospect.