4results about How to "Improve escape ability" patented technology

The invention provides an early warning device adopting four-color light combination, which comprises a base, an earthquake information receiver, a light early warning assembly, a sound early warning assembly and a control system are integrated on the base, and the earthquake information receiver is used for receiving earthquake early warning information sent by a seismic bureau; the light early warning assembly comprises a plurality of early warning lamps with the same or different shapes and colors; the sound early warning assembly comprises a controller and a loudspeaker; the control system has a manually set light early warning rule, and controls the early warning lamps at different positions to flicker and the sound early warning assembly to give an alarm according to different earthquake grades; according to the earthquake early-warning level feedback system, visual and tactile signals can be provided at the same time, a good warning effect on various people, especially color blindness and deaf people, is also achieved, operation is more convenient, the earthquake early-warning level feedback speed is greatly increased, and the earthquake early-warning level feedback effect is improved. And people can conveniently respond in time.

This invention discloses an adaptive sliding mode control method for tower cranes based on an improved fruit fly optimization algorithm, comprising the following steps: Step 1): Designing an extended state observer to observe the load swing angle state; Step 2): Designing an adaptive sliding mode controller, feeding back the observed swing angle state to the adaptive sliding mode controller, which will enable the trolley to be precisely positioned while suppressing load swing angle oscillation; Step 3): Optimizing the parameters of the adaptive sliding mode controller through an improved fruit fly optimization algorithm, thereby improving the controller's control effect. This invention uses a combination of a linear extended observer and an adaptive sliding mode controller, which has the advantages of easy swing angle observation, simple physical implementation of the controller, and good control effect; in terms of parameter tuning, an improved fruit fly algorithm is used to strengthen the cooperation among fruit flies, avoid getting trapped in local optima, and improve the controller's control effect.

This invention relates to a type I collagen truncated peptide and its delivery system. The amino acid sequence of the α1 chain of the type I collagen truncated peptide includes the sequence shown in SEQ ID NO.1; the amino acid sequence of the α2 chain of the type I collagen truncated peptide includes the sequence shown in SEQ ID NO.2. This invention achieves in situ expression of the type I collagen truncated peptide in vivo through a specially designed expression method, enabling self-sufficient supplementation of type I collagen. The truncated type I collagen retains the first half of the type I collagen sequence and part of the C-terminal sequence, thereby preserving the main functional components and the ability to form a triple helix, improving synthesis efficiency and mRNA stability; the removal of some metalloprotein binding sites increases its stability, and the absence of amino acid mutations ensures safety.

The invention relates to the technical field of biological medicine, in particular to a polypeptide with high transfection efficiency, a peptide library, a polypeptide-nucleic acid compound and application thereof, the polypeptide with high transfection efficiency comprises five peptide modules A, X, B, C and Y, and the five peptide modules A, X, B, C and Y are sequentially connected through peptide bonds to form the polypeptide; the X peptide module is any one of an X1 peptide module and an X2 peptide module, and the Y peptide module is any one of a Y1 peptide module and a Y2 peptide module; the peptide library comprises a plurality of polypeptides, and the peptide library is helpful for quickly finding carrier formulas for different nucleic acid drugs, so that the construction of a drug delivery carrier platform can be better guided; the polypeptide-nucleic acid compound comprises polypeptide and nucleic acid, in the assembling and forming process of the polypeptide-nucleic acid compound, the molar ratio of protonated nitrogen of the polypeptide to phosphate groups of the nucleic acid is 15: 1-30: 1, and the polypeptide-nucleic acid compound is expected to be applied to medicine preparation.