2results about How to "Improve escape ability" patented technology

This invention discloses an adaptive sliding mode control method for tower cranes based on an improved fruit fly optimization algorithm, comprising the following steps: Step 1): Designing an extended state observer to observe the load swing angle state; Step 2): Designing an adaptive sliding mode controller, feeding back the observed swing angle state to the adaptive sliding mode controller, which will enable the trolley to be precisely positioned while suppressing load swing angle oscillation; Step 3): Optimizing the parameters of the adaptive sliding mode controller through an improved fruit fly optimization algorithm, thereby improving the controller's control effect. This invention uses a combination of a linear extended observer and an adaptive sliding mode controller, which has the advantages of easy swing angle observation, simple physical implementation of the controller, and good control effect; in terms of parameter tuning, an improved fruit fly algorithm is used to strengthen the cooperation among fruit flies, avoid getting trapped in local optima, and improve the controller's control effect.

This invention relates to a type I collagen truncated peptide and its delivery system. The amino acid sequence of the α1 chain of the type I collagen truncated peptide includes the sequence shown in SEQ ID NO.1; the amino acid sequence of the α2 chain of the type I collagen truncated peptide includes the sequence shown in SEQ ID NO.2. This invention achieves in situ expression of the type I collagen truncated peptide in vivo through a specially designed expression method, enabling self-sufficient supplementation of type I collagen. The truncated type I collagen retains the first half of the type I collagen sequence and part of the C-terminal sequence, thereby preserving the main functional components and the ability to form a triple helix, improving synthesis efficiency and mRNA stability; the removal of some metalloprotein binding sites increases its stability, and the absence of amino acid mutations ensures safety.