Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Solasodine hydriodate and its preparation method and its uses in medicine

A technology of solanamine hydroiodide and medicinal residues, which is applied in the field of preparation of Australian solanamine hydroiodide, and can solve the problems that the related information of Australian solanamine hydroiodide has not yet been found.

Inactive Publication Date: 2008-02-13
刘芯辰
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Existing domestic and foreign solanum solanum, Australian solanum and yellow fruit solanum chemical constituents, Australian solanamine, Australian solanamine hydrochloride, Australian solanamine sulfate, Australian solanamine organic acid salt and its extraction and preparation method and its application in medicine Applied patents and reports, but no relevant information about Australian solanamine hydroiodide has been found

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Solasodine hydriodate and its preparation method and its uses in medicine
  • Solasodine hydriodate and its preparation method and its uses in medicine
  • Solasodine hydriodate and its preparation method and its uses in medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0052] Embodiment 1 prepares Australian solanamine hydroiodide with Solanum nigrum as raw material

[0053] With reference to Fig. 1, take nightshade fruit as raw material to prepare Australian solanamine hydroiodide, the preparation method is as follows:

[0054] (1) Take by weighing 1000kg of Solanum nigrum fruit harvested in late September, remove sundries, and pulverize solid-liquid separation with a refiner to obtain medicinal juice and medicinal residues. The dregs are leached twice with 1% hydrochloric acid aqueous solution, the solid-liquid ratio is 1:1, and the solid-liquid separation is obtained with a refiner. Combine the concoction and the infusion, leave it to settle, take the supernatant and filter, add 20% NaOH aqueous solution to pH 7.5 when the filtrate is heated to 80°C, and then add (NH 4 ) 2 CO 3Saturate the aqueous solution to pH 8, cool and settle, remove the supernatant, and centrifuge the turbid liquid to obtain the paste-like crude total alkaloids. ...

Embodiment 2

[0057] Embodiment 2 prepares Australian solanamine hydroiodide with yellow fruit eggplant as raw material

[0058] With reference to Fig. 1, preparation method is as follows:

[0059] (1) Take by weighing 1000kg of huangguoqie fruit harvested in late September, remove sundries, and pulverize with a refiner for solid-liquid separation to obtain medicinal juice and medicinal residues. The medicinal dregs are leached twice with 3% formic acid aqueous solution, the solid-liquid ratio is 1:1, and the solid-liquid separation is obtained with a refiner. Combine the medicinal juice and infusion, place it for sedimentation, take the supernatant and filter it, and add Ca(OH) when the filtrate is heated to 80°C 2 After the saturated aqueous solution reaches pH 7.5, add (NH 4 ) 2 CO 3 Saturate the aqueous solution to pH 8, cool and settle, remove the supernatant, and centrifuge the turbid liquid to obtain the paste-like crude total alkaloids.

[0060] (2) Dissolve the crude total alk...

Embodiment 3

[0062] Embodiment 3 prepares Australian solanamine hydroiodide with Australian solanum fruit as raw material

[0063] With reference to Fig. 1, preparation method is as follows:

[0064] (1) Weigh 1000kg of Australian eggplant fruits harvested in late September, remove foreign matter, and pulverize with a refiner for solid-liquid separation to obtain medicinal juice and medicinal residues. The medicinal dregs were leached twice with 4% acetic acid aqueous solution, the solid-liquid ratio was 1:1, and the solid-liquid separation was obtained by a refiner. Combine the medicinal juice and infusion, place it for sedimentation, take the supernatant and filter it, and add Ca(OH) when the filtrate is heated to 80°C 2 After saturating the solution to pH 7.5, add (NH 4 ) 2 CO 3 Saturate the aqueous solution to pH 8, cool and settle, remove the supernatant, and centrifuge the turbid liquid to obtain the paste-like crude total alkaloids.

[0065] (2) Dissolve the crude total alkaloi...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The present invention provides one new kind of compound, solasodine hydriodide, with obvious anticancer and asthma relieving effects, less toxic side effect, stable property and high dissolubility. The molecular expression is shown. The present invention also relates to the preparation process of solasodine hydriodide with black nightshade, Australia eggplant or yellowfruit nightshade as material. The preparation process includes acid leaching and precipitating to obtain total alkaloid. The preparation process of the present invention has low reagent cost, no environmental pollution, short production period, high product purity and other advantages. The present invention also relates to the application of solasodine hydriodide in preparing medicine for treating cancer and relieving asthma, etc.

Description

technical field [0001] The present invention relates to a compound with anti-cancer and anti-asthma activities, solanamine hydroiodide, a preparation method of solanamine hydroiodide and a new drug source using solanamine hydroiodide as a class of new drugs. Anti-cancer, anti-asthma and other medical applications. Background technique [0002] Existing domestic and foreign solanum solanum, Australian solanum and yellow fruit solanum chemical constituents, Australian solanamine, Australian solanamine hydrochloride, Australian solanamine sulfate, Australian solanamine organic acid salt and its extraction and preparation method and its application in medicine Application patents and reports, but no relevant information on Australian solanamine hydroiodide has been found. Contents of the invention [0003] The present invention provides a kind of Australian solanamine hydroiodide with strong anti-cancer and anti-asthma activity, small toxic and side effects, stable properties...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C07J71/00A61K31/58A61P35/00A61P11/06
Inventor 刘良刘芯辰崔淑华
Owner 刘芯辰
Features
  • Generate Ideas
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com