Dripping pills of abastard speedwell and its preparation process

A technology of Lemahui and Huidi Pills, which is applied in the field of Lemahui Droppills and its preparation, can solve the problems that are not conducive to improving the ability of patients to seek medical treatment, the bioavailability of the first-pass effect of the liver and intestines, and the overall health level of the society. The effect of improving bioavailability, high bioavailability, and drug safety

Inactive Publication Date: 2008-07-30
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In addition, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking, which affect the quality of the drug. Efficacy also directly affects the therapeutic effect
At the same time, conventional oral dosage forms often produce relatively large dust pollution during the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause certain pollution to the environment.
The production process of conventional oral preparations is also relatively complicated, and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society

Method used

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Examples

Experimental program
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Embodiment Construction

[0030] Now with several groups of specific examples, the preparation method of Lemahui dripping pills of the present invention will be further described.

[0031] [Group 1: Trials with a single substrate]

[0032] 1. Preparation of the medicinal extract: according to [Preparation Method 1], the dry powder of the extract containing the active pharmaceutical ingredient of Lemahui is prepared in advance for later use;

[0033] 2. Substrate: polyethylene glycol 1000 , polyethylene glycol 4000 , polyethylene glycol 6000 , polyethylene glycol 10000 , polyethylene glycol 20000 , Span 40, polyoxyl 40 stearate, poloxamer, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac;

[0034] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0035] 4. Prepare according to the process given in [Preparation Method] 4-7 ​​to obtain Lemahui Dropping Pills of different specifications.

[0036] [test results]

[0037] Experiment 1: ...

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PUM

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Abstract

Disclosed is a dripping pill for treating pulmonary abscess, dyspnea, chronic cough and uropenia. The objective of the invention is to provide a medicinal composition having the advantages of high biological availability, quick-speed medicine release, quick-speed effect, higher medicinal content, accurate administration dosage, low price, no acute allergic reaction or adverse effect, and facilitated carrying. The drop pill is prepared from Chinese medicinal material Lemahui, and medicinal carrying agent as the base material.

Description

technical field [0001] The present invention relates to a kind of medicine composition that has the effects of clearing away heat and detoxifying, relieving cough and resolving phlegm, diuresis, etc., and is used for the treatment of diseases such as carbuncle sore, lung abscess, cough and asthma, chronic cough, hot stranguria and astringent pain, dysuria, etc. The invention relates to an oral preparation of a pharmaceutical composition prepared by using the traditional Chinese medicine Lemahui as a raw material. Background technique [0002] According to the ministerial drug standard WS 3 - Lemahui Injection, prepared by the preparation method given in B-2775-97, has the functions of clearing heat and detoxification, relieving cough and reducing phlegm, diuretic, etc. The pure traditional Chinese medicine injection for chronic cough, hot stranguria, astringent pain, difficulty urinating and other diseases has been clinically verified and has definite curative effect. It is...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/80A61P11/14A61P11/10A61P11/00A61P13/00A61P17/02
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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