Unlock instant, AI-driven research and patent intelligence for your innovation.

Medicinal composition for treating aphronesia and preparing process thereof

A composition and drug technology, applied in the field of medicine, can solve the problems of inconvenient use, poor patient compliance, frequent administration times, etc.

Inactive Publication Date: 2009-08-05
TIANJIN TASLY PHARMA CO LTD
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the common preparations, the active ingredients therein face a series of problems, such as frequent clinical administration, inconvenient use, poor patient compliance, etc.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Medicinal composition for treating aphronesia and preparing process thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] Example 1 Preparation of ordinary tablets

[0056] Take the following medicinal materials: Astragalus 16.7g, Salvia 16.7g, Ligusticum chuanxiong 10g, Atractylodes Rhizome 10g, Shichangpu 10g, Coptis 3.3g, Borneol 0.0667g;

[0057] Take Astragalus and Dan in 10 times the amount of water, reflux for extraction 2 times, 1.5 hours each time, the extract is filtered, and set aside; Chuanxiong, Atractylodes, Acorus calamus, add 10 times the amount of water to extract the volatile oil with a volatile oil extractor for 8 hours, and the volatile oil is standby. Filter out the water extract, add 10 times the amount of water to extract the medicinal residue for 1.5 hours, combine the water extracts, filter and combine with the astragalus and salvia extracts and concentrate under reduced pressure to 1ml approximately equal to 1g crude drug, let cool, add 95% ethanol to make alcohol The concentration is 60%. After standing overnight, filter to recover ethanol to 1ml approximately equal ...

Embodiment 2

[0060] Take the following medicinal materials: Astragalus 16.7g, Danshen 16.7g, Ligusticum chuanxiong 10g, Cangzhu 10g, Shichangpu 10g, Coptis 3.3g, and Borneol 0.0667g;

[0061] Astragalus and Dan were added with 10 times the amount of water, refluxed for 2 times, 1.5 hours each time, the extract was filtered and reserved; Ligusticum chuanxiong, Atractylodes, Shichangpu added 10 times the amount of water to extract the volatile oil with a volatile oil extractor for 8 hours, the volatile oil for standby, filtered The water extract is extracted, and the medicinal residue is extracted with 10 times the amount of water for 1.5 hours. The water extracts are combined, filtered and combined with the extract of Astragalus and Salvia and concentrated under reduced pressure to 1ml, which is about 1g crude drug. Let cool and add 95% ethanol to make the alcohol concentration. After standing overnight, filter, recover ethanol to 1ml approximately equal to 3g crude drug, add 95% ethanol to mak...

Embodiment 3

[0065] Take the following medicinal materials: Astragalus 25.5g, Danshen 25.5g, Ligusticum chuanxiong 15g, Cangzhu 15g, Shichangpu 15g, Coptis 7.5g, and Borneol 0.8g;

[0066] Take astragalus and pill with 14 times the amount of water, reflux for extraction 2 times, 3 hours each time, the extract is filtered, and set aside; Chuanxiong, Cangzhu, Shichangpu add 12 times the amount of water to extract the volatile oil with a volatile oil extractor for 12 hours, and the volatile oil is standby. The water extract is filtered out, and the medicine residue is extracted with 12 times the amount of water for 3 hours. The water extracts are combined, filtered and combined with the astragalus salvia extract and concentrated under reduced pressure to 1ml, which is about 1.5g crude drug. Let cool, add 98% ethanol to make The alcohol concentration is 60%. After standing overnight, filter, recover ethanol to 1ml approximately equal to 4g crude drug, add 95% ethanol to make the alcohol concentrat...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a pharmaceutical composition, specifically, it is composed of astragalus, salvia miltiorrhiza, chuanxiong, etc., and hydroxypropyl methylcellulose is added to make a gel matrix tablet. The invention also discloses a preparation method thereof.

Description

Technical field [0001] The invention belongs to the field of medicine, and specifically relates to a gel matrix tablet for treating dementia and a preparation method thereof. Background technique [0002] Dementia is a common senile disease, and it is also recognized as a refractory disease in today’s medical field. According to the World Health Organization, 10% of the elderly over the age of 65 have mental disabilities, and 60% of them have dementia. As the age increases, the incidence of dementia tends to increase substantially. Dementia in the senile period can be divided into two categories: chronic and acute according to the speed of the development of symptoms: chronic dementia accounts for about 80% of senile dementia, and is also called senile chronic brain syndrome. It includes senile dementia, vascular dementia and mixed dementia where both exist. There are also some rare dementias, such as subacute spongiform encephalopathy and Parkinson's disease. Acute dementia is a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/888A61K36/718A61K36/53A61K36/481A61K36/284A61K36/236A61K31/045A61K9/20A61P25/28
Inventor 郑永锋范立君
Owner TIANJIN TASLY PHARMA CO LTD