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Composition for treating gout

A composition and gout technology, applied in the direction of drug combinations, plant raw materials, medical preparations containing active ingredients, etc., can solve the problems of slow onset of action and inferior effect to colchicine, improve safety and overcome adverse reactions. , the effect of increasing the scope of application

Inactive Publication Date: 2009-08-26
孙雁群
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] However, the above two drugs have a slow onset of action and often take more than 10 minutes to take effect, so the effect of using alone is not as good as colchicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0022] Obtain optimum prescription with orthogonal test below, the present invention is described further by embodiment.

[0023] The preparation method of capsule:

[0024] Cortex Phellodendri fluid extract is extracted according to the existing extraction technology, and each gram of fluid extract is equivalent to 20 grams of crude drug.

[0025] 1. Pass oxaprozin, starch or cellulose through an 80-mesh sieve, and set aside;

[0026] 2. Weigh oxaprozin, phellodendron fluid extract, and starch according to the formula and put them into a mixer for mixing;

[0027] 3. The mixed material is filled on the automatic capsule filling machine;

[0028] 4. Polish the filled capsules on a capsule polishing machine;

[0029] 5. Pack the polished capsules in a polyolefin plastic bottle.

[0030] Tablet preparation method:

[0031] 1. Pass ketoprofen, starch or cellulose through an 80-mesh sieve, and set aside;

[0032] 2. Take by weighing ketoprofen, Cortex Phellodendri fluid extr...

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PUM

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Abstract

The invention discloses a composition for treating gout, which belongs to the technical field of gout treatment. The main component is non-steroidal anti-inflammatory drug oxaprozin or ketoprofen, and Cortex Phellodendri is added to oxaprozin or ketoprofen The original drug, the weight ratio of oxaprozin or ketoprofen to the original drug of Cortex Phellodendri is 1: 160-320, and the present invention overcomes the difficult problem of slow onset of non-steroidal anti-inflammatory drugs used alone, increasing The application range of non-steroidal anti-inflammatory drugs in the treatment of gout has been expanded. At the same time, the toxicity of non-steroidal anti-inflammatory drugs and traditional Chinese medicine Cortex Phellodendri is far less than that of colchicine, and the safety has been greatly improved, overcoming colchicine and allopurinol. There are many adverse reactions when used in combination, and the side effects on patients are large.

Description

technical field [0001] The invention belongs to the technical field of gout treatment, in particular to the technical field of treating gout with Chinese and western medicine compositions. Background technique [0002] Gout is a disease caused by purine metabolic disorders. Typical clinical manifestations include increased blood uric acid, acute or chronic gouty arthritis with recurrent acute attacks and other symptoms. [0003] Western medicine believes that uric acid is the final product of purine metabolism. The pathogenesis of gout is excessive blood uric acid caused by abnormal uric acid metabolism. Reasons such as decreased uric acid excretion. In recent years, due to the improvement of living conditions, people eat a lot of purine-rich foods, coupled with unhealthy work and lifestyle, the accumulation of uric acid in the human body, the incidence of gout has increased significantly, and the disease is acute, and the affected joints are painful Unbearable. [0004] ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/756A61K31/421A61K31/192A61P19/06
Inventor 孙雁群
Owner 孙雁群