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Hericiaceae contained Jianweiling capsules for stomach disease

A technology of soft capsules and Hericium head is applied in the direction of capsule delivery, medical preparations derived from fungi medical raw materials and inactive ingredients, etc. problem, to achieve good stability and bioavailability, improve bioavailability, and enhance the effect of curative effect

Active Publication Date: 2009-12-09
山西旺龙药业集团有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Due to the slow drug release rate and low bioavailability of capsules, the clinical response is unstable

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Preparation of active ingredients:

[0041] Hericium erinaceus culture extract 100g sea octopus 80g

[0042] Corydalis (made) 40g Baishao (made) 40g

[0043] A total of 1000 capsules can be made

[0044] The method is as follows

[0045] The above six flavors, Hericium erinaceus culture extract is taken from Hericium erinaceus culture, decocted twice with water, 2 hours each time, combined decoction, filtered, and the filtrate was separated and purified with macroporous adsorption resin, or directly concentrated to a relatively high temperature. The density is 1.04, let it stand for 24 hours, filter, and concentrate under reduced pressure the extract with a relative density of 1.30; after extracting the other five flavors such as squid and octopus with water, separate and purify them with a macroporous adsorption resin column, or crush them into fine powder, sieve, Mix evenly, sterilize, and mix evenly with the above-mentioned extract to obtain the pharmaceutical act...

Embodiment 2

[0047] Preparation of soft capsules:

[0048] Pharmaceutical active ingredient 100g soybean oil 200g beeswax 8g made into 1000 capsules

[0049] Preparation: Dissolve beeswax in soybean oil and stir evenly to obtain the content matrix. Take the active ingredients of the medicine and feed them according to the prescription ratio. The active ingredients of the medicine are added into the content matrix, stirred evenly, and then pulverized by colloid milling to obtain the content. Compress soft capsules, dry, and make 1000 capsules, to get final product.

Embodiment 3

[0051] Preparation of soft capsules:

[0052] Active ingredient 100g, soybean oil 300g, beeswax 9g, make 1000 capsules

[0053] Preparation: Dissolve beeswax in soybean oil and stir evenly to obtain the content matrix. Take the active ingredients of the medicine and feed them according to the prescription ratio. The active ingredients of the medicine are added into the content matrix, stirred evenly, and then pulverized by colloid milling to obtain the content. Compress soft capsules, dry, and make 1000 capsules, to get final product.

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PUM

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Abstract

A Chinese medicine in the form of softgel for treating gastrosis is prepared from 6 Chinese medicinal materials including hedgehog hydnum, white peony root, cyperus tuber, liquorice, etc.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine preparation for treating stomach diseases, in particular to the reformation of the dosage form of Hericium Hericium Jianweiling soft capsule, which is prepared by processing six traditional Chinese medicines. Background technique: [0002] Hericium Jianweiling Soft Capsules are based on Hericium Jianweiling Capsules by changing the dosage form. Hericium Jianweiling Capsules have the effects of soothing the liver and stomach, regulating qi and relieving pain. For liver-stomach disharmony, epigastric and hypochondrium pain, vomiting and acid regurgitation; chronic gastritis belongs to the above-mentioned syndromes. The drug is currently on the market. [0003] Due to the slow drug release rate and low bioavailability of capsules, the clinical response is unstable. Soft capsule is to dissolve the active ingredients of medicine in liquid solvent, make it into a uniform liquid state, and then fill i...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/48A61K36/8905A61K36/71A61K36/66A61K36/484A61K36/06A61K35/56A61K47/44A61K47/34A61P1/04A61K35/618A61K47/10
Inventor 王建辉
Owner 山西旺龙药业集团有限公司