Chinese medicine combination with whitening function and uses thereof

A composition and technology of traditional Chinese medicine, applied in traditional Chinese medicine composition with whitening function and its application field, can solve the problems of large side effects and easy decomposition, and achieve the effects of lightening pigmentation, promoting metabolism, and less skin irritation

Active Publication Date: 2010-02-10
克劳丽化妆品股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, hydroquinone is banned due to excessive side effects, kojic acid and its derivatives have strong whitening effect, but they are easy to decompose when exposed to light and heat

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Example 1: Experimental method and whitening effect evaluation

[0019] 1. Sample preparation

[0020] The crude drug of traditional Chinese medicine was dried overnight in an oven, crushed and passed through a 40-mesh sieve, added 10 times of 50% ethanol, heated and refluxed for 3 times, each time for 1 hour. Combine the extracts and filter while hot. Ethanol was recovered from the filtrate under reduced pressure and placed. The precipitate was removed by centrifugation, the supernatant was eluted by D101 macroporous resin, the 70% ethanol eluate was collected, concentrated under reduced pressure and vacuum, and the Chinese medicine extract was obtained. The extract was dissolved in dimethyl sulfoxide to prepare a solution with a concentration of 1%, and the following experiments were carried out.

[0021] 2. Determination of free radical scavenging effect

[0022] Add 2 mL of Chinese herbal medicine extract and 2 mL of diphenylpicrylphenylhydrazine (DPPH) solution...

Embodiment 2

[0039] Embodiment 2: Chinese medicine composition

[0040] The Chinese medicine composition (I) with whitening function is composed as follows:

[0041] Scutellaria baicalensis extract 10%

[0042] Knotweed Extract 50%

[0043] Paeonol Extract 40%

[0044] The traditional Chinese medicine composition (II) with whitening function is composed as follows:

[0045] Skullcap Extract 50%

[0046] Knotweed Extract 10%

[0047] Paeonol Extract 40%

[0048] The traditional Chinese medicine composition (III) with whitening function is composed as follows:

[0049] Skullcap Extract 45%

[0050] Knotweed Extract 45%

[0051] Paeonolium Extract 10%

[0052] The traditional Chinese medicine composition (IV) with whitening function is composed as follows:

[0053] Skullcap Extract 30%

[0054] Knotweed Extract 20%

[0055] Paeonolium Extract 50%

Embodiment 3

[0056] Example 3: Whitening Cream

[0057] Component w / %

[0058] A Glyceryl monostearate 6.00

[0059] Propylene glycol 5.50

[0060] Stearic acid 4.00

[0061] Triethanolamine 0.70

[0062] White mineral oil 10.00

[0063] Methylparaben 1.50

[0064] Isopropyl myristate 10.00

[0065] Polydimethylsiloxane 2.00

[0066] B Chinese medicine composition (I) 1.00

[0067] Deionized water 59.30

[0068] Preparation: Heat components A and B to 70°C under stirring, until all are dissolved and mixed evenly. Add B to A component under stirring at 70°C until W / Q type emulsion is formed. After stirring evenly, cool to room temperature.

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PUM

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Abstract

The invention discloses a Chinese herbal medicine composition with whitening function and the application, comprising extracts of scutellaria, polygonum cuspidate, and cortex moutan. The Chinese herbal medicine composition can be used as skin whitening preparation for external application, and has the advantages of inhibiting the formation of melanogenesis, improving pigmentation, and whitening skin.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and its application, in particular to a traditional Chinese medicine composition with whitening function and its application. Background technique [0002] The color of the skin mainly depends on the amount of melanin contained in the skin. Melanin is produced by melanocytes in the epidermis, and its synthesis is affected by a variety of enzymes in the cell, including tyrosinase, dopachrome isomerase, 5,6-dihydroxyindole-2-carboxylic acid (DHICA ) oxidase, etc. Among them, tyrosinase is the main rate-limiting enzyme, and the activity of this enzyme determines the amount of melanin formed. In addition, the synthesis of melanin is also affected by factors such as ultraviolet rays and free radicals. [0003] Most of the current whitening products mainly focus on inhibiting tyrosinase. These existing agents are unsatisfactory in terms of stability, side effects, effects and the like. ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/97A61K36/539A61K36/704A61K36/71A61Q19/02
Inventor 张目朱少娟严泽民段明星
Owner 克劳丽化妆品股份有限公司
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