Unlock instant, AI-driven research and patent intelligence for your innovation.

Traditional Chinese medicine preparation for treating coronary heart disease and angina pectoris and its preparing process

A technology for angina pectoris and traditional Chinese medicine for coronary heart disease, which is applied in the field of traditional Chinese medicine preparations and its preparation, can solve the problems of low extraction rate of the effective components of Paeonia lactiflora, the needs of both doctors and patients in a single dosage form, and low drug bioavailability, and achieves improved bioavailability, The effect of improving social and economic benefits and improving solubility

Active Publication Date: 2010-02-10
SHANDONG BUCHANG PHARMA
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The Chinese Patent Gazette discloses a patent application titled "a Chinese patent medicine for treating angina pectoris of coronary heart disease" with application number 93103012.9. It does not disclose specific preparations, so it is difficult to implement in the process of preparing specific preparations according to it. As a pharmaceutical preparation, the final product enters the market in a specific dosage form and is used by patients. Since the application does not have a more specific product preparation, Therefore, whether the implementation is feasible, whether the use is effective, etc. are all questions
Although the implementation and use of capsules and tablets have been basically solved; but in the actual application process, we found that its therapeutic effect is not ideal; due to the preparation method, the extraction rate of active ingredients of Radix Paeoniae Alba is low, and the biological The utilization is low and the onset time is long; in addition, although these two preparation dosage forms can meet certain market demands, they still cannot fully meet the needs of both doctors and patients due to the single dosage form, especially some patients are unwilling to take capsules and tablet

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine preparation for treating coronary heart disease and angina pectoris and its preparing process
  • Traditional Chinese medicine preparation for treating coronary heart disease and angina pectoris and its preparing process
  • Traditional Chinese medicine preparation for treating coronary heart disease and angina pectoris and its preparing process

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0081] Example 1 of the present invention: 1000 parts of Radix Paeoniae Alba are chopped and extracted with 75-80% ethanol, and after purification of the macroporous resin, 5 parts of ginsenosides and 25 parts of micronized silica gel are added as suspending agent and grinding aid, 50 Part soybean oil is used as a dispersion medium, and soft capsules are made according to a conventional process.

Embodiment 2

[0082] Example 2 of the present invention: 3000 parts of Radix Paeoniae Alba were chopped and extracted with 75-80% ethanol, and after the macroporous resin was purified, 25 parts of ginsenosides, 45 parts of polyethylene glycol 400 and 300 parts of polyethylene glycol were added 4000 is a dispersant, which is made into soft capsules according to conventional techniques.

Embodiment 3

[0083] Example 3 of the present invention: 2,500 parts of Radix Paeoniae Alba are broken, added 75-85% ethanol to extract, the extract is concentrated under reduced pressure, added water to precipitate, filtered, DM-130 macroporous adsorption resin on the filtrate, 85-95% Ethanol elution, the eluent is decompressed to recover ethanol, dried, and crushed into fine powder; gelatin, water and glycerin are melted and kept warm for later use; After the parts are mixed evenly, add 85-95% ethanol to make a soft material, dry, pulverize, add 200 parts of soybean oil and stir evenly, grind into a uniform sticky paste with a colloid mill, degas under reduced pressure, and press into soft capsules. Take orally, 2 capsules at a time, 2 times a day.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a Chinese herbal preparation for treating coronary angina pectoris and the preparation method. The preparation is mainly prepared by ginseng stems and leaves saponins and whitepeony root; the White Peony Root is extracted through ethanol; dropping pills are produced by purified macroporous resin plus the ginseng stems and leaves saponins. The preparation has the function of promoting blood circulation by removing blood stasis, replenishing qi and relieving pain, applicable to chest distress, cardiodynia, heart-throb and short breath all resulted from deficiency of qi and blood stasis. Compared with the prior art, the invention is characterized in excellent process, high bioavailability and evident efficacy.

Description

[0001] This application is a divisional application of 200410081237.3, the filing date: November 5, 2004, and the name of the invention is: a traditional Chinese medicine preparation for treating coronary heart disease angina pectoris and its preparation method. technical field [0002] The invention relates to a traditional Chinese medicine preparation and a preparation method thereof, in particular to a traditional Chinese medicine preparation for treating coronary heart disease angina pectoris and a preparation method thereof, belonging to the technical field of medicines. Background technique [0003] Coronary heart disease and angina pectoris are common and frequently-occurring diseases that seriously endanger the health of human beings, especially middle-aged and elderly people. At present, there is no good curative drug. The Chinese Patent Gazette discloses a patent application titled "a Chinese patent medicine for treating angina pectoris of coronary heart disease" wi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/71A61K36/258A61K9/20A61P9/10
Inventor 赵涛
Owner SHANDONG BUCHANG PHARMA