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Compound traditional Chinese medicine with antibiotic and anti-inflammatory function, and its preparing method

A compound traditional Chinese medicine, antibacterial and anti-inflammatory technology, which is applied in the direction of antibacterial drugs, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve problems such as adverse reactions and inability to meet clinical needs, and achieve medical needs, good curative effect, and ingredients simple effect

Inactive Publication Date: 2010-05-19
湖南恒生制药股份有限公司
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  • Application Information

AI Technical Summary

Problems solved by technology

Although there are many anti-infective traditional Chinese medicines on the market, they are far from meeting the clinical needs, such as Sanhuang tablets, Chuanhuning injection, etc. Although the curative effect has been recognized by patients, they still have certain limitations, such as Chuanhuning Injection can be used clinically for the treatment of acute inflammation, the effect is good, but there are many reports of adverse reactions

Method used

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  • Compound traditional Chinese medicine with antibiotic and anti-inflammatory function, and its preparing method
  • Compound traditional Chinese medicine with antibiotic and anti-inflammatory function, and its preparing method
  • Compound traditional Chinese medicine with antibiotic and anti-inflammatory function, and its preparing method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] Take by weighing 2500g of King Kongteng, 150g of Huangtengsu (equivalent to 3000g of Huangteng) and 2500g of Rhizoma Rhizoma, and prepare into tablets according to the following method:

[0058] A. Take Daxueteng in proportion, add 10 times the amount, 7.5 times the amount of water to soak for 1 hour, decoct 2 times, 1.5 hours each time, filter, combine the filtrate, static precipitation filter, take the filtrate and concentrate to a relative density of 1.00 ~1.05 (thermal measurement), vacuum dried into a dry paste.

[0059] B. Take King Kong vine in proportion, add water to decoct twice, each time for 2 hours, combine the decoction, filter, concentrate the filtrate to an appropriate amount, add ethanol to make the solution contain 50% ethanol, let it stand for 24 hours, filter The ethanol is recovered from the filtrate, concentrated to an appropriate amount, and vacuum-dried to a dry paste, that is, the extract of King Kongtaw.

[0060] C. Grinding the dry paste obta...

Embodiment 2

[0062] Take by weighing 100g of King Kongteng extract (equivalent to 1500g of King Kongteng), 200g of palmatine (equivalent to 4000g of Huangteng) and 4000g of Rhizoma Rhizoma, and prepare capsules as follows:

[0063] A. Take Daxueteng in proportion, add 8 times the amount, 5 times the amount of water to soak for 1.5 hours, decoct 2 times, 2 hours each time, filter, combine the filtrate, static precipitation and filter, take the filtrate and concentrate to a relative density of 1.10 ~1.15 (thermal measurement), vacuum dried into a dry paste;

[0064] B. Grinding the dry paste obtained in step A and the extract of King Kong vine in proportion into a fine powder, and mixing it with the palmatine in proportion, adding auxiliary materials such as magnesium stearate, pregelatinized starch, and stone powder Appropriate amount, granulated with 65% ethanol, granulated, mixed evenly, and filled. Prepare 1000 capsules.

Embodiment 3

[0066] Take by weighing 3000g of King Kongteng, 1800g of Huangteng and 2400g of Sageteng, and prepare into capsules as follows:

[0067] A. Proportionally weigh Daxueteng, Huangteng and Daxueteng, add 10 times or 8 times the amount of water, soak for 1 hour, decoct 2 times, 1.5 hours each time, filter, combine the filtrate, static precipitation and filtration, take the filtrate Concentrate to an appropriate amount, and vacuum-dry to form a dry paste;

[0068] B. Grinding the dry paste obtained in step A into fine powder, adding auxiliary materials such as menthol to prepare 1000 ml of lotion for external use.

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Abstract

A Chinese medicine for treating various infectious diseases, especially the gynecological inflammation, is prepared from bock greenbrier root or its extract and fibraurea root or its extract. Its preparing process is also disclosed.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and relates to an antibacterial and anti-inflammatory compound traditional Chinese medicine and a preparation method thereof. Background technique [0002] With the continuous growth of my country's economy, population growth and aging, and the continuous improvement of people's living standards, the hospital market for anti-infective drugs has reached 34.5 billion yuan, ranking first in the hospital drug list with a 26.5% share. [0003] Antibiotics are the most important component of infection drugs, accounting for nearly 90% of all anti-infection drugs. However, in recent years, with the long-term and large-scale clinical application of antibiotics, the phenomenon of bacterial drug resistance has become more and more serious. Human beings have realized the serious consequences of overuse of antibiotics. Therefore, it has the reputation of "green antibiotics" and is made of " "Antib...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/896A61P31/04A61K31/4745
Inventor 朱志宏卜振军杨静
Owner 湖南恒生制药股份有限公司
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