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Transdermal plaster prepn of Tramadol hydrochloride

A technology of tramadol hydrochloride and transdermal patch, which is applied in the fields of sheet-like delivery, drug equipment, nervous system diseases, etc. It can solve the problems that the transdermal speed cannot meet the treatment requirements and restrict the area of ​​transdermal preparations, etc.

Inactive Publication Date: 2007-08-22
陶燃
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The dosage of the transdermal drug delivery system is determined by the effective drug release area and the transdermal rate of the drug. Due to their physical and chemical properties, the transdermal rate of most drugs cannot meet the treatment requirements, and the practical application restricts the transdermal preparation. the area of

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Embodiment 1, preparation contains the transdermal patch tablet of tramadol hydrochloride. The method comprises the steps of dissolving the medicine in water, adding it to a dressing, stirring to form a gel, and packaging to make a gel-like transdermal patch.

Embodiment 2

[0013] Embodiment 2. Using gel transdermal patch during treatment with ultrasonic conductivity meter.

[0014] Put the patch prepared in Example 1 into the corresponding placement position of the treatment head, and press it firmly. Remove the anti-adhesive paper on the concave surface of the patch, stick the patch together with the treatment head to the skin of the treatment area, and remove it after the treatment is over.

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PUM

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Abstract

The present invention discloses one kind of transdermal plaster preparation of Tramadol hydrochloride. The plaster preparation of Tramadol hydrochloride is used in ultrasonic administrating system, ion introducing administrating system, electroporating administrating system and high pressure gas administrating system, to treat various kinds of chronic pain, post-operational pain and cancer pain. It may be also used in drug addiction eliminating treatment.

Description

technical field [0001] The invention relates to a transdermal patch preparation for various acute and chronic pains, surgical pains, cancer pains, and drug rehabilitation. Further, the patent of the present invention relates to the use of low-frequency ultrasonic drug delivery system to treat various acute and chronic pains, surgical pains, cancer pains, and to treat drug addiction. Background technique [0002] Pain is one of the most common human diseases, and millions of people around the world suffer from it. There are at least 6 million pain patients in Beijing alone. At present, various acute and chronic pains are mainly treated with oral drugs for symptomatic treatment. Oral drugs can severely stimulate the gastrointestinal tract, and the curative effect is short and the effect is not obvious. Especially for some local pains, oral drugs are difficult to reach, which makes the effect worse. . Therefore, there is a need to provide a drug in a new dosage form that prod...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/137A61K9/70A61P25/04A61P25/36A61M37/00
Inventor 陶燃
Owner 陶燃
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