Stable liquid agent for external use

A liquid, stable technology, applied in skin care preparations, toiletry preparations, cosmetics, etc., can solve the problem of separation of tocopherol and water

Inactive Publication Date: 2007-10-24
KOWA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, even if the silk powder is dispersed with a thickener, there is a problem that tocopherol, which is an oil component, is separated from water

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035]0.2 g of tocopheryl acetate and 0.5 g of hydrogenated soybean phospholipid (Phospholipon 90H: phospholipid) were added to 5 g of 1,3-butanediol, and stirred well at 80° C. for mixing. 30 g of purified water was added to this solution, and it was fully stirred and mixed (prepared solution A).

[0036] 0.05 g of carboxyvinyl polymer (Syntarene L: Wako Pure Chemical Industries, Ltd.), 0.01 g of sodium edetate, and 0.1 g of methyl p-hydroxybenzoate were added to 60 g of purified water, and the mixture was thoroughly stirred and mixed. Add an appropriate amount of potassium hydroxide as a neutralizing agent to the solution so that the pH is 6, stir well, and after mixing, add preparation solution A and 0.5 g of silk powder (Silukugen G powder: Ichimaru Farcos), stir well, and mix, Air bubbles were removed under reduced pressure, water was added so that the total amount would be 100 g, and an aqueous liquid preparation for external use was obtained.

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Abstract

Disclosed is a liquid agent for external use wherein a tocopherol, a silk powder, a phospholipid such as a hydrogenated phospholipid, a carboxyvinyl polymer and water are mixed and the water content is set at 79-99% by weight. Such a liquid agent for external use is prevented from separation of the tocopherol and sedimentation of the silk powder, thereby achieving a stable dispersion state.

Description

technical field [0001] The present invention relates to a liquid preparation for external use which is excellent in usability and which is stable over time without separation or sedimentation of components. Background technique [0002] It is well known that tocopherol is effective in preventing skin aging due to its antioxidative effect and blood circulation promoting effect. In addition, silk powder has skin protection and moisturizing effects, and at the same time has a smooth feeling of use. Therefore, a formulation having both of these effects is expected by mixing these two components, and its practical implementation is expected. [0003] However, tocopherol is an oil component, and silk powder is a solid component. Therefore, when it is made into a liquid preparation for external use, there is a problem of separation and sedimentation of components over time. [0004] To solve the above problems, in order to disperse tocopherol, there is known a method of emulsifyi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/67A61K8/81A61K8/55A61K8/64
CPCA61K8/987A61Q19/00A61K8/678A61K8/553A61K8/55A61K8/67A61K8/72
Inventor 竹前和久
Owner KOWA CO LTD
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