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Medicine composition for treating chronic active hepatitis and early-stage hepatocirrhosis and preparation method thereof

A technology of active hepatitis and composition, which is applied in the field of traditional Chinese medicine, can solve the problems of low HBsAg negative conversion rate, long taking time, large side effects, etc., and achieve the effect of scientific and reasonable composition, easy acceptance and good curative effect

Active Publication Date: 2010-06-16
BEIJING ASIA EAST BIO PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no specific virus-clearing drug. Although interferon and lamivudine are internationally recognized drugs with relatively positive anti-viral efficacy, due to the low rate of HBsAg negative conversion, the side effects are large, the price is high, the taking time is long, and the recurrence rate is high. The rate is as high as 70% to 80%, which is difficult for patients to accept

Method used

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  • Medicine composition for treating chronic active hepatitis and early-stage hepatocirrhosis and preparation method thereof
  • Medicine composition for treating chronic active hepatitis and early-stage hepatocirrhosis and preparation method thereof
  • Medicine composition for treating chronic active hepatitis and early-stage hepatocirrhosis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0115] Yinchen 400g Banzhilian 400g Poria cocos 400g Curcuma 100g Zeilan 200g

[0116] Safflower 100g Bupleurum 100g Amber 40g White Peony 400g

[0117] The above nine flavors are decocted with water for 1-3 times, each time for 1-3 hours, the decoctions are combined, concentrated to a clear paste with a relative density of 1.20-1.35 (50°C), and ethanol is added to make the alcohol content reach 60-70%. Stand still for 20-48 hours, recover ethanol, concentrate to a relative density of 1.25-1.40 (50°C), add appropriate amount of auxiliary materials, and prepare various preparations for clinical application, such as: granules, capsules, tablets, oral liquids, soft drinks, etc. Capsules, dropping pills, dispersants, effervescent agents, sustained-release preparations, etc.

Embodiment 2

[0119] Yinchen 400g Banzhilian 400g Poria cocos 400g Curcuma 100g Zeilan 200g

[0120] Safflower 100g Bupleurum 100g Amber 40g White Peony 400g

[0121] The above nine flavors are decocted twice with water, each time for 2 hours, the decoctions are combined, concentrated to a clear paste with a relative density of 1.30 (50°C), and ethanol is added to make the alcohol content reach 65%, and the ethanol is recovered after standing for 24 hours. Concentrate to a relative density of 1.35 (50°C), take 1 part of clear paste, 3 parts of sucrose, and 1 part of dextrin, make granules, dry, and obtain;

Embodiment 3

[0123] Yinchen 100g Banzhilian 100g Poria cocos 100g Curcuma 25g Zeilan 50g

[0124] Safflower 25g Bupleurum 25g Amber 10g White Peony 100g

[0125] The above nine flavors are decocted twice with water, each time for 2 hours, the decoctions are combined, concentrated to a clear paste with a relative density of 1.30 (50°C), and ethanol is added to make the alcohol content reach 65%, and the ethanol is recovered after standing for 24 hours. Concentrate to a relative density of 1.35 (50°C), take 1 part of clear paste, 3 parts of sucrose, and 1 part of dextrin, make granules, dry, and obtain;

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Abstract

The invention is concerned with the Chinese traditional medicine combination for clearing away the heat-evil and expelling superficial evils, consists of capillary artemisia, Scutellaria barbata D.Don, tuckahoe, radix curcumae, herba lycopi, safflower, bupleurum, amber, and paeonia lactiflora pallas, which can treat clearing hepatitis B virus and early liver cirrhosis. The invention is also concerned with the preparation method and preparation of the Chinese traditional medicine combination.

Description

technical field [0001] The invention provides a pharmaceutical composition for treating hepatitis and a preparation method thereof, in particular relates to a traditional Chinese medicine composition for chronic active hepatitis and early liver cirrhosis, and belongs to the technical field of traditional Chinese medicine. Background technique [0002] The clinical symptoms of hepatitis B virus chronic active hepatitis are generally more obvious than those of persistent hepatitis. The main manifestations are gradual decline in working ability, fatigue, poor appetite, greasy feeling, persistent and obvious abdominal distension, often bleeding gums and epistaxis. Some patients often have low-grade fever, menstrual disorders, sexual dysfunction or decline, and some patients also have extrahepatic damage such as arthritis, nephritis, diabetes, and Sjogren's syndrome. Early liver cirrhosis refers to clinically without any specific symptoms or signs, and liver function tests have ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61K9/08A61K9/10A61K9/14A61K9/16A61K9/20A61K9/46A61K9/48A61P1/16A61P31/20A61K35/10
Inventor 付立家付建家
Owner BEIJING ASIA EAST BIO PHARMA CO LTD
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