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A set of medicinal compositions for treating melancholia and preparation method

A composition and technology for depression, applied in the direction of drug combination, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve problems such as side effects and calm down patients

Inactive Publication Date: 2008-06-04
张作光
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These drugs all have different degrees of side effects. Studies have shown that "the Fuan suppository contained in these drugs has an effect on balancing the body's functions, but more often than not, they still cannot calm the patient down.

Method used

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  • A set of medicinal compositions for treating melancholia and preparation method
  • A set of medicinal compositions for treating melancholia and preparation method
  • A set of medicinal compositions for treating melancholia and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] See attached figure 1 , 10 kg of ginseng (in accordance with the provisions of the Pharmacopoeia of the People’s Republic of China) was crushed and decocted with 75% ethanol solution, separated and purified by upper column chromatography, and dried to obtain 0.4 kg of ginseng extract; 18 kg of white peony (in accordance with the " The Pharmacopoeia of the People's Republic of China) decocted with water, separated and purified by upper column chromatography, and dried to obtain 1.44 kg of white peony extract; the extracts obtained in the above steps were mixed and crushed to obtain the pharmaceutical extract composition of the present invention.

Embodiment 2

[0042] See attached figure 2 , Directly add 4.8 grams of ginsenoside (R g1 +R e +R b1 ), 20 grams of paeoniflorin are mixed and crushed to obtain the pharmaceutical extract composition of the present invention.

Embodiment 3

[0044] 0.6 kg of ginseng and 1.4 kg of white peony are mixed and superfinely crushed to obtain the pharmaceutical composition of the present invention. Experimental Example 1 The effect of Example 1 on the tail suspension experiment in mice

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Abstract

The invention discloses a drug composition containing ginseng and white paeony root as raw materials used for treating depression. The invention also discloses the preparation method thereof. The experiment confirms that the drug composition can significantly reduce the tail suspending motionless time and forcing swimming motionless time of the subject mice, thus concluding that the composition of the invention has the efficacy of anti-experimental depression.

Description

Technical field [0001] The present invention relates to a set of pharmaceutical compositions for treating depression made with ginseng and white peony as raw materials, which can be used as medicines, nutrients and health foods. [0002] The invention also relates to a method for preparing the above-mentioned pharmaceutical composition for treating depression. Background technique [0003] Depression is a common disease. According to statistics, about 25% of women in the general population have experienced depression in their lifetime, and about 10% of men have experienced depression (by Zhang Chunxing: "Modern Psychology"). Information provided by the World Health Organization: The incidence of depression in the world is about 11%. There are currently about 340 million mentally depressed patients worldwide, and this number is still on the rise. The survey found that depression will increase in the next 20 years It is the second most common disease in the world. [0004] At prese...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61P25/24
Inventor 张作光
Owner 张作光
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