External preparation, method of applying external preparation, iontophoresis device, and percutaneous patch

A technology of external preparations and ionic electricity, which is applied in the direction of treatment, electrotherapy, sheet delivery, etc., can solve the problems of not giving the following enlightenment, inequity, etc.

Inactive Publication Date: 2008-06-11
TITI ELLEBEAU INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the cationic surfactant in Patent Document 3 is not equivalent to ion-exchange resins or hydrophilic polymers with ion-exchange functions. In addition, Patent Document 3 does not give the following revelation, that is, cationic surfactants and charged Combination of administration of positive and negative arbitrary drug ions

Method used

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  • External preparation, method of applying external preparation, iontophoresis device, and percutaneous patch
  • External preparation, method of applying external preparation, iontophoresis device, and percutaneous patch
  • External preparation, method of applying external preparation, iontophoresis device, and percutaneous patch

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Embodiment Construction

[0078] Embodiments of the present invention will be described below.

[0079] FIG. 1 is an iontophoresis device Xa of the present invention, which is an iontophoresis device for administering a drug whose active ingredient is dissociated into a cation (for example, lidocaine as an anesthetic, morphine hydrochloride as an anesthetic, etc.) An explanatory diagram of the basic structure of Xa.

[0080] As shown in the figure, the iontophoresis device Xa of the present invention includes a working electrode structure 1a, a non-working electrode structure 2a, and a power source 3 as major components (components).

[0081] The working electrode structure 1a is equipped with: an electrode member 11, which is connected to the positive pole of the power supply 3; an electrolyte solution holding part 12, which holds the electrolyte solution provided to keep in contact with the electrode member 11; an anion exchange membrane 13a, which is arranged on the The front of the electrolyte hol...

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Abstract

The invention relates to a method for forming a coating film Mi to M4 which is formed by a drug including a hydrophilic macromolecule base agent and an ion exchanging resin dispersed in the hydrophilic macromolecule base agent on the skin, or a coating film Mi to M4 is formed by a hydrophilic macromolecule drug having the ion exchanging function. The electric ion penetration treatment is carried out with the coating film, thereby not only restraining the release of organism load ion from the organism skin and remaining the good contact state between the functional-pole structure and the non-functional-pole structure and the skin, but also increasing the feeding efficiency of the drug.

Description

technical field [0001] The present invention relates to an external preparation used for drug administration using iontophoresis, a coating method of the external preparation, and an iontophoresis device used in combination with the external preparation. Background technique [0002] The iontophoresis device generally has: an active electrode structure, which holds a solution of a drug that dissociates the medicinal effect ingredient into positive or negative drug ions by dissolution; a non-active electrode structure, which has the effect of the counter electrode of the active electrode structure , in the state where these two structures are in contact with the skin of a living body (human or animal), a voltage of the same polarity as that of the drug ion is applied to the active electrode structure (the first conductivity type voltage), and the non-active A voltage of opposite polarity (second conductivity type voltage) is applied to the polar structure to administer drug i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K47/30A61K9/70A61K47/32A61K47/34A61K47/36A61K47/38A61K47/42A61N1/30A61M35/00
CPCA61K9/7023A61K9/0009A61N1/0444A61K9/7084A61N1/0492
Inventor 松村昭彦中山鸠夫松村健彦秋山英郎辻和之芝田勉谷冈明彦皆川美江
Owner TITI ELLEBEAU INC
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