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External use traditional Chinese medicine preparation for curing gynecology inflammation and method of preparing the same

A traditional Chinese medicine preparation and a technology for gynecological inflammation, which are applied in the field of external use traditional Chinese medicine preparations for treating gynecological inflammation and their preparation, and achieve the effects of wide indication range, good curative effect and stable curative effect.

Active Publication Date: 2008-09-03
GUIZHOU BAILING GRP PARMACEUTIAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, there is no pure Chinese medicine effervescent suppository product for the treatment of gynecological diseases on the market

Method used

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  • External use traditional Chinese medicine preparation for curing gynecology inflammation and method of preparing the same
  • External use traditional Chinese medicine preparation for curing gynecology inflammation and method of preparing the same
  • External use traditional Chinese medicine preparation for curing gynecology inflammation and method of preparing the same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0345] Example 1: Sophora flavescens 200g, Fructus Cnidii 150g, Phellodendron cortex 150g, Bo Luohui 120g, Red soil Poria cocos 300g, pomegranate peel 100g, dry alum 30g, polyethylene glycol-2000 1028g, polyethylene glycol-4000 115g, tartaric acid 200g , sodium bicarbonate 200g, Tween-80 of 1% preparation amount.

[0346] a, preparation of extract dry powder:

[0347] Take dried alum and beat it into fine powder for later use, take Cnidium fruit and soak it in 12 times the amount of water for 6 hours, heat and reflux for extraction for 6 hours, and obtain Cnidium volatile oil, water extract liquid and medicinal residue; , mixed with Boluohui and Fructus Cnidii medicinal residues, soaked overnight with 8 times the amount of 70% ethanol, extracted 3 times at 70°C, each time for 1 hour, and pressed the extract with a 400-mesh filter cloth while it was hot filter, and combine to obtain filtrate 1 for subsequent use. The obtained dregs were extracted once with 6 times the amount ...

Embodiment 2

[0354] Example 2: Sophora flavescens 50g, Fructus Cnidii 300g, Cortex Phellodendri 150g, Boluohui 250g, Poria cocos red soil 450g, pomegranate peel 100g and dry alum 150g, polyethylene glycol-4000 800g, citric acid 100g, potassium bicarbonate 300g, preparation Volume 0.5% Tween-80.

[0355] a, preparation of extract dry powder: take dry alum and beat into fine powder for later use, Fructus Cnidii extracts volatile oil with water, volatile oil and water extract for subsequent use; Sophora flavescens, Phellodendron Phellodendri, Bo Luohui, Red soil Poria cocos and Fructus Cnidii dregs use 5 times the amount Soak in 50% ethanol overnight, then extract 4 times at 80°C for 2 hours each time, filter the obtained extract while it is hot with a 200-mesh filter cloth, combine the filtrates to obtain filtrate 1 for later use, and use 10 times the amount of water to obtain the dregs at 70°C Extract once, combine the obtained extract and Fructus Cnidii water extract and filter while hot w...

Embodiment 3

[0357] Example 3: Sophora flavescens 100g, Fructus Cnidii 350g, Cortex Phellodendri 200g, Bo Luohui 250g, Red soil Poria cocos 500g, pomegranate peel 150g and dry alum 100g, polyethylene glycol-6000 3000g, malic acid 400g, sodium carbonate 150g, preparation amount 2% Tween-80.

[0358] a, preparation of extract dry powder: get dried alum and beat into fine powder for subsequent use, get Fructus Cnidii and soak 6 hours with 10 times the amount of water, heat and reflux extract for 6 hours, obtain Fructus Cnidii volatile oil, water extract and dregs; Sophora flavescens, Phellodendron Phellodendron and Red Smilax Poria cocos are made into the coarsest powder, combined with Boluohui and Cnidium chinensis medicine dregs, soaked in 8 times the amount of 90% ethanol overnight, extracted twice at 70°C, each time for 1 hour, and the extract is filtered through a 300-mesh filter cloth. Filtrate hot, combine to obtain filtrate 1 for later use, extract the obtained medicinal residues twic...

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Abstract

The invention provides a traditional Chinese medicine externally applied preparation for the treatment of gynecological diseases and a preparation method thereof. The traditional Chinese medicine externally applied preparation is prepared by lightyellow sophora root, common cnidium fruit, amur corktree bark, pink plumepoppy herb, red earth Indian buead, liquid extract which is extracted from the effective parts of pomegranate rind and dried alum super-fine powder, wherein, an effervescent suppository preparation is prepared by adding polyethylene glycol, organic acid, hydrogen carbonate salt or carbonate salt or Tween 80 in the ingredients. The invention takes the lightyellow sophora root and the common cnidium fruit as monarch drugs, the amur corktree bark, the pink plumepoppy herb and the red earth Indian buead are taken as auxiliary drugs, the pomegranate rind and the dried alum are taken for assistance, the effective rate for the treatment of gynecological diseases can achieve more than 90 percent, and the invention has no stimulus, toxicity or side effects, thus being the safe and reliable pure traditional Chinese medicine externally applied preparation. The effervescent suppository preparation is further provided, the usage is convenient, the patient compliance is increased, and the preparation process is relatively simple.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine pharmacy, in particular to an external Chinese medicinal preparation for treating gynecological inflammation and a preparation method thereof. Background technique [0002] Vaginitis (vaginitis) is one of the common and frequently-occurring diseases in women. It occurs in different age groups of women. At present, the number of women aged 18-50 in China is 340 million, accounting for about 28% of China's total population, including about 100 million in cities and 240 million in rural areas. According to the survey, about 41% of women suffer from gynecological inflammatory diseases to varying degrees, and the incidence rate of married women is as high as 80%. [0003] Gynecological inflammation has a great impact on women's life and work. At present, antibiotics are the main treatment for this disease, but the toxic side effects and drug resistance have a negative impact on pa...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61K9/02A61K9/00A61K9/10A61K9/46A61K47/34A61P15/00A61P15/02A61K33/06A61K47/10
Inventor 蔡少青董立莎张亚洲陈晓昱陈嵘
Owner GUIZHOU BAILING GRP PARMACEUTIAL CO LTD
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