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Externally used Chinese medicine extract for treating liver ascites and preparation method thereof

A technology of extract and traditional Chinese medicine, which is applied in the field of traditional Chinese medicine extract and its preparation for external treatment of hepatic ascites, which can solve problems such as difficulty in comprehensive implementation, not necessarily continuous effectiveness, high requirements for liver function and surgery itself

Inactive Publication Date: 2008-09-24
302 MILITARY HOSPITAL OF CHINA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, the long-term use of western medicine to treat ascites is not only a potential "safety hazard", but also may not be "sustainably effective"
[0004] In recent years, with the advancement of medical technology, a series of "special therapies" based on surgical operations have emerged. These therapies can quickly eliminate or relieve symptoms, but there are also "safety hazards" and are "universal, economical, and patient-compliant." "sex" also needs to be improved
For example: a large amount of ascites and albumin supplementation, although this method is simple and effective, but requires a large amount of protein and is expensive, and a large amount of ascites may induce hepatic coma; autologous ascites intravenous reinfusion, this method is mild and effective Little impact on the body, low cost, but strict indications, not suitable for patients with ascites infection, malignant transformation and bleeding tendency
Portosystemic shunt, or transjugular portocaval stent shunt through intervention, these methods have high requirements on the patient's liver function and the operation itself, and it is difficult to fully implement

Method used

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  • Externally used Chinese medicine extract for treating liver ascites and preparation method thereof
  • Externally used Chinese medicine extract for treating liver ascites and preparation method thereof
  • Externally used Chinese medicine extract for treating liver ascites and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0155] Weigh 9kg Panax notoginseng, 14kg Kansui, and 22kg cinnamon, grind them into coarse powder, and set aside;

[0156] The cinnamon coarse powder is put into the extraction kettle and the temperature of the dissociation kettle I is 35°C, 6Mpa, the temperature of the dissociation kettle II is 25°C, and the condition of 5Mpa is extracted, and the discharge of the dissociation kettle I and the dissociation kettle II is collected, That is, cinnamon volatile oil;

[0157] The mixture of notoginseng, kansui and cinnamon dregs is reflux extracted with 70% ethanol, extracted twice, adding 6 times the amount of solvent each time, extracting for 1.5 hours, and the extract of the mixture of notoginseng, kansui and cinnamon is obtained;

[0158] The Chinese medicine extract of the present invention is obtained by mixing cinnamon volatile oil with extracts from the mixture of notoginseng, kansui and cinnamon dregs, and drying.

Embodiment 2

[0160] Weigh 5kg Panax notoginseng, 5kg Kansui, and 10kg cinnamon, grind them into coarse powder, and set aside;

[0161] The cinnamon coarse powder is put into the extraction kettle and the temperature of the dissociation kettle I is 35°C, 6Mpa, the temperature of the dissociation kettle II is 25°C, and the condition of 5Mpa is extracted, and the discharge of the dissociation kettle I and the dissociation kettle II is collected, That is, cinnamon volatile oil;

[0162] The mixture of notoginseng, kansui and cinnamon dregs is reflux extracted with 70% ethanol, extracted twice, adding 6 times the amount of solvent each time, extracting for 1.5 hours, and the extract of the mixture of notoginseng, kansui and cinnamon is obtained;

[0163] The Chinese medicine extract of the present invention is obtained by mixing cinnamon volatile oil with extracts from the mixture of notoginseng, kansui and cinnamon dregs, and drying.

Embodiment 3

[0165] Weigh 15kg Panax notoginseng, 15kg Gansui, 30kg coarse powder of cinnamon, set aside;

[0166] The cinnamon coarse powder is put into the extraction kettle and the temperature of the dissociation kettle I is 35°C, 6Mpa, the temperature of the dissociation kettle II is 25°C, and the condition of 5Mpa is extracted, and the discharge of the dissociation kettle I and the dissociation kettle II is collected, That is, cinnamon volatile oil;

[0167] The mixture of notoginseng, kansui and cinnamon dregs is reflux extracted with 70% ethanol, extracted twice, adding 6 times the amount of solvent each time, extracting for 1.5 hours, and the extract of the mixture of notoginseng, kansui and cinnamon is obtained;

[0168] The Chinese medicine extract of the present invention is obtained by mixing cinnamon volatile oil with extracts from the mixture of notoginseng, kansui and cinnamon dregs, and drying.

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Abstract

The invention relates to an external traditional Chinese medicine extractive for treating liver ascites and a preparation method, in particular to a Chinese medicine extractive for treating liver ascites and a preparation method and belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine extractive for treating liver ascites is prepared by notoginseng, euphorbia kansui and cinnamon. The cinnamon is extracted by supercritical CO2 and then cinnamon naphtha and dregs are obtained. The cinnamon dregs together with notoginseng and euphorbia kansui are conducted a back extraction by ethanol and then an extractive is obtained. The extractive is then mixed with the cinnamon naphtha and concentrated and then an extractive for treating liver ascites is obtained. The traditional Chinese medicine extractive for treating liver ascites has a tonifying effect on the qi-blood deficiency caused by ascites due to cirrhosis and the rooted deficiency due to the phlegm stagnation of qi, blood and water.

Description

Technical field: [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to an external Chinese medicine extract for treating liver ascites and a preparation method thereof. Background technique: [0002] Cirrhotic ascites is a worldwide disease, regardless of nationality, race, age, or gender. In recent years, hundreds of thousands of people around the world have died of this disease every year, and it is showing an upward trend. It is mainly manifested as abdominal pain. The abdominal wall is protruding, tight and shiny, which makes it difficult for the patient to walk, and may cause many fatal diseases. Although the patient undergoes formal treatment, ascites is still difficult to disappear and is life-threatening. It has become an important research topic in the medical field. [0003] Western medicine selects appropriate diuretics and portal pressure-reducing drugs based on liver function and serum potassium, sodi...

Claims

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Application Information

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IPC IPC(8): A61K36/54A61P1/16
Inventor 肖小河张萍周旭付强任永申
Owner 302 MILITARY HOSPITAL OF CHINA
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