Stable medicine combination

A kind of composition and medicine technology, applied in the field of stable pharmaceutical composition
CN101336920BActive Publication Date: 2013-06-05NANJING CHIA TAI TIANQING PHARMA
2 Cites 7 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
NANJING CHIA TAI TIANQING PHARMA
Publication Date
2013-06-05

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
Patent Text Reader

Abstract

The invention relates to a stable oral pharmaceutical composition, particularly to a pharmaceutical composition comprising rosuvastatin calcium, micropowder silica gel and pharmaceutically-acceptable adjuvants, and a preparation method and an application thereof.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The present invention relates to a stable pharmaceutical composition, in particular to rosuvastatin calcium: bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[formazan A stable pharmaceutical composition of (methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid]calcium salt (as shown in formula I).

[0002]

[0003] Formula I Background technique

[0004] Rosuvastatin calcium is a potent 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCoA reductase) inhibitor, which can be used in the treatment of hypercholesterolemia, hyperlipoproteinemia and atherosclerosis It is better than other statins on the market in reducing low-density lipoprotein (LDL-C) and increasing high-density lipoprotein (HDL-C), and it is well tolerated and safe. For "super statin".

[0005] One disadvantage of rosuvastatin calcium is that it is easily degraded under certain circumstances, such as in a higher temperature or higher humidity environment, and th...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More