Solid preparation containing ibuprofen and tranexamic acid
A technology of tranexamic acid and preparation, applied in the field of solid preparations, can solve the problems of small analgesic effect and the like
Inactive Publication Date: 2009-01-28
KOWA CO LTD
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Problems solved by technology
However, since ibuprofen has side effects such as gastrointestinal disturbances, and its analgesic effect is small, it has been studied in combination with various drugs
Method used
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Experimental program
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Embodiment 1
Embodiment 2
Embodiment 3
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The invention provides a solid preparation restricted under high-temperature preserving condition and containing brufen as well as tranexamic acid. The solid preparation contains organic acid or ester or salt thereof.
Description
technical field [0001] The present invention relates to a solid preparation comprising ibuprofen and tranexamic acid whose swelling is inhibited under high-temperature storage conditions. Background technique [0002] Ibuprofen is widely used as a non-steroidal anti-inflammatory drug (NSAID), anti-inflammatory and analgesic for chronic joint rheumatism, joint pain and arthritis, neuralgia and neuritis, low back pain and other diseases and symptoms Effective, in addition to cold syndrome, acute bronchitis, acute exacerbation of chronic bronchitis anti-inflammatory and antipyretic, etc. are also effective. However, since ibuprofen has side effects such as gastrointestinal disturbances and has a small analgesic effect, a combination preparation with various drugs has been studied. [0003] For example, antipyretic analgesics in which ibuprofen is mixed with aniline derivative antipyretic analgesics such as busetin (see Patent Document 1), and preparations in which ibuprofen is...
Claims
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IPC IPC(8): A61K31/195A61K31/192A61K9/00A61K47/12A61P29/00
CPCA61K47/12A61K9/20A61K31/192A61K31/195A61P29/00A61K2121/00
Inventor 薄井俊树下川达张川岛弘行
Owner KOWA CO LTD
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