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Underfill detection system for electrochemical biosensor

A biosensor, an understudied technology, applied in the direction of material electrochemical variables, scientific instruments, instruments, etc.

Active Publication Date: 2013-08-14
ASCENSIA DIABETES CARE HLDG AG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

This delay may require replacing the sensor strip with a new sensor strip and a new biofluid sample

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  • Underfill detection system for electrochemical biosensor
  • Underfill detection system for electrochemical biosensor
  • Underfill detection system for electrochemical biosensor

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Embodiment Construction

[0051] The present invention provides an underfill detection system for a biosensor. The underfill detection system improves the accuracy and precision of the biosensor in determining whether a sample of a biological fluid is large enough to analyze one or more analytes. The underfill detection system applies a test excitation signal to the sample deposited in the biosensor. The test stimulus is switched to one or more different amplitudes. The sample generates a test output signal in response to the test stimulus signal. When the sample is not large enough for accurate and / or precise analysis, transitioning the test excitation signal to a different amplitude changes the test output signal. The underfill detection system measures and compares the test output signal to one or more underfill thresholds to determine whether an underfill condition exists. Biosensors can be utilized to determine the concentration of one or more analytes such as glucose, uric acid, lactate, chole...

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Abstract

A biosensor has an underfill detection system that determines whether a sample of a biological fluid is large enough for an analysis of one or more analytes. The underfill detection system applies an excitation signal to the sample, which generates an output signal in response to the excitation signal. The underfill detection system switches the amplitude of the excitation signal. The transition of the excitation signal to a different amplitude changes the output signal when the sample is not large enough for an accurate and / or precise analysis. The underfill detection system measures and compares the output signal with one or more underfill thresholds to determine whether an underfill condition exists.

Description

[0001] References to related applications [0002] This application claims priority to U.S. Provisional Application No. 60 / 797,128, entitled "Underfill Detection System for a Biosensor," filed May 3, 2006, the contents of which are hereby incorporated The entire content is for reference only. Background technique [0003] Biosensors typically provide analysis of biological fluids such as whole blood, urine or saliva. In general, a biosensor analyzes a sample of a biological fluid to determine the concentration of one or more analytes in the biological fluid, such as glucose, uric acid, lactate, cholesterol, or bilirubin. Such analysis can be used to diagnose and treat physiological abnormalities. For example, a diabetic patient may use a biosensor to measure glucose levels in the blood to adjust diet and / or medication. If the sample size is not large enough, the biosensor may be underfilled when used. An underfilled biosensor may not provide accurate analysis of the biolog...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N27/30G01N33/487
CPCG01N35/00029G01N35/1016G01N27/3274G01N27/3271
Inventor 伍焕平克里斯廷·D·尼尔森
Owner ASCENSIA DIABETES CARE HLDG AG