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Compound oral medicament composition for treating respiratory diseases of pig and cattle

A technology of respiratory tract and composition, applied in the field of compound oral pharmaceutical composition, which can solve problems such as large dosage, reduced therapeutic effect, food safety and drug resistance during use

Active Publication Date: 2011-05-18
QINGDAO VLAND BIOTECH INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0017] The existing combination of antibiotics and flunixin meglumine on the market includes oxytetracycline or the compound preparation of florfenicol and flunixin meglumine. Food safety issues and drug resistance have arisen, and the therapeutic effect has been severely reduced, and the combination of Tulathromyin and flunixin meglumine has not been reported

Method used

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  • Compound oral medicament composition for treating respiratory diseases of pig and cattle
  • Compound oral medicament composition for treating respiratory diseases of pig and cattle
  • Compound oral medicament composition for treating respiratory diseases of pig and cattle

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0091] Telamectin-flunixin meglumine compound oral pharmaceutical composition:

[0092] 100ml contains:

[0093] Tulathromycin: 5.0g

[0094] Flunixin meglumine: 4.15g

[0095] Citric acid: 0.15g

[0096] Thioglycerol: 0.5g

[0097] Thioglycolic acid: 0.1g

[0098] Sodium edetate: 0.5g

[0099] Water for injection to : 100ml

[0100] HCL or NaOH solution to adjust the pH to 4.5-5.5

[0101] making process:

[0102] Add 80ml of distilled water into a 200ml beaker, add telamycin, flunixin meglumine, stir and add citric acid until dissolved, add thioglycerol, thioglycolic acid and sodium edetate dissolved in a small amount of distilled water in sequence, and use HCL Or adjust the pH to 4.5-5.5 with NaOH solution, and dilute to the mark with distilled water. The resulting solution was a colorless to light yellow clear solution.

Embodiment 2

[0104] Telamectin-flunixin meglumine compound oral pharmaceutical composition:

[0105] 100ml contains:

[0106] Tulathromycin: 1.0g

[0107] Flunixin meglumine: 0.83g

[0108] Citric acid: 0.15g

[0109] Thioglycerol: 0.5g

[0110] Thioglycolic acid: 0.1g

[0111] Sodium edetate: 0.5g

[0112] Water for injection to : 100ml

[0113] HCL or NaOH solution to adjust the pH to 4.5-5.5

Embodiment 3

[0115] Telamectin-flunixin meglumine compound oral pharmaceutical composition:

[0116] 100ml contains:

[0117] Tulathromycin: 35.0g

[0118] Flunixin meglumine: 29.05g

[0119] Citric acid: 0.15g

[0120] Thioglycerol: 0.5g

[0121] Thioglycolic acid: 0.1g

[0122] Sodium edetate: 0.5g

[0123] Water for injection to : 100ml

[0124] HCL or NaOH solution to adjust the pH to 4.5-5.5

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Abstract

The invention relates to a compound oral medicine composition for treating respiratory disease of animals, in particular to a compound oral medicine composition for treating the respiratory disease of pigs and cattle. The composition contains tulathromycin with effective quantity and nonsteroidal antipyretic and analgesic.

Description

Technical field: [0001] The invention relates to a compound oral pharmaceutical composition for treating animal respiratory diseases, in particular to a compound oral pharmaceutical composition for treating pig and bovine respiratory diseases. Background technique: [0002] Respiratory diseases are one of the more difficult-to-control infectious diseases in animal husbandry. They are seriously harmful to animal husbandry and cause huge economic losses worldwide. In China, the annual losses of pig and cattle industries due to respiratory diseases amount to hundreds of billions Yuan. The economic losses caused are mainly due to respiratory diseases that easily lead to the death of animals, weight loss, decreased milk production, and huge treatment costs and reduction in feeding efficiency. [0003] Swine respiratory disease, also known as swine respiratory disease complex (SRDC), is a general term for respiratory diseases caused by multiple factors. It is caused by the intera...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7052A61K9/00A61K45/00A61K31/44A61P11/00
Inventor 殷生章王巧玲
Owner QINGDAO VLAND BIOTECH INC