Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Yam dispensing granule as well as preparation method and quality control method thereof

A technology of formula granules and yam, which is applied in the field of yam formula granules and its preparation, and can solve problems such as difficulties in spectrum analysis

Inactive Publication Date: 2009-07-08
BEIJING KANGRENTANG PHARMA
View PDF0 Cites 10 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the fact that Chinese herbal medicines, herbal pieces and Chinese patent medicines are much more complex mixture systems than western medicines, it is difficult to analyze the spectra, so that conventional infrared spectroscopy has not been able to play its due role in the quality control and management of traditional Chinese medicines for a long period of time. the role of

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Yam dispensing granule as well as preparation method and quality control method thereof
  • Yam dispensing granule as well as preparation method and quality control method thereof
  • Yam dispensing granule as well as preparation method and quality control method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Embodiment 1: Chinese yam formula granule

[0037] Take 100kg of yam decoction pieces, add 800kg of water, extract for 2 hours, that is, the first decoction; after the first decoction, add 800kg of water to the dregs, extract for 1.5 hours, that is, the second decoction; combine the two decoction liquids, and concentrate under reduced pressure to a relative density of 1.05-1.10 The concentrated solution is preheated at 45°C, the inlet air temperature is 180°C, the material pump speed is 550 rpm, the outlet air temperature is 80°C, and the air delivery temperature is 45°C, and it is spray-dried to obtain yam spray-dried powder; Add its own weight portion 0-5% auxiliary material dextrin in the powder; the yam spray-dried powder is under the condition that the main pressure roller pressure is 5MPa, the side pressure roller pressure is 0.5MPa, the spindle speed is 400 rpm, and the feeding voltage is 120V. Dry granulation to obtain 20-60 mesh yam formula granules, each gram ...

Embodiment 2

[0038] Embodiment 2: Chinese yam formula granule

[0039] Take 100kg of yam decoction pieces, add 1000kg of water, extract for 2 hours, that is, the first decoction; after the first decoction, add 600kg of water to the dregs, extract for 1 hour, that is, the second decoction; combine the two decoction liquids, and concentrate under reduced pressure to a relative density of 1.00-1.05 The concentrated solution is preheated at 50°C, the inlet air temperature is 170°C, the material pump speed is 600 rpm, the outlet air temperature is 75°C, and the air delivery temperature is 50°C, and it is spray-dried to obtain yam spray-dried powder; Add 5-15% of its own weight of auxiliary material dextrin to the powder; dry granulation under the conditions of main pressure roller pressure 6MPa, side pressure roller pressure 0.4MPa, spindle speed 450 rpm, and feeding voltage 110V , to get 20-60 mesh yam formula granules, each gram of yam formula granules is equivalent to 7 grams of crude drug; ...

Embodiment 3

[0041] Embodiment 3: Chinese yam formula granule

[0042] Take 100kg of yam decoction pieces, add 1400kg of water, extract for 2.5 hours, that is, the first decoction; after the first decoction, add 1100kg of water to the dregs, extract for 2.5 hours, that is, the second decoction; combine the two decoction liquids, and concentrate under reduced pressure to a relative density of 1.10-1.15 The concentrated solution is preheated at 45°C, the inlet air temperature is 170°C, the material pump speed is 600 rpm, the outlet air temperature is 75°C, and the air delivery temperature is 50°C and spray-dried to obtain yam spray-dried powder; Add the lactose of its own weight portion 15-25% in the powder; Dry granulation under the condition that the main pressure wheel pressure is 4MPa, the side pressure wheel pressure is 0.4MPa, the spindle speed is 500 rev / min, and the feeding voltage is 130V, to obtain 20-60 mesh yam formula granules, each gram of yam formula granules is equivalent to ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a yam prescription granule, a preparation method and a quality control method thereof. The yam prescription granule takes yam herbal pieces prepared for decoction as the raw material and is prepared by the processes of twice extraction by water, reduced pressure concentration, spray drying, and the like; each gram of the yam prescription granule corresponds to 5-10g of crude drug dosage; the quality of both yam herbal pieces prepared for decoction and yam prescription granule is identified by infrared fingerprint spectra. The yam prescription granule of the invention has integral and advanced preparation process and specific and controllable quality control standard, wherein, the advanced process can be realized and the detection method related to the quality standard is scientific, advanced and fast and convenient with strong feasibility. Experiments show that the decoction composed by the yam prescription granule of the invention contains the same ingredients as the herbal pieces mixedly decocted liquor containing yam of the classical prescription, the prescription granule process of bulk composition is realized and the process of the invention is reasonable; furthermore, the invention applies the technology of infrared fingerprint spectra to the quality control of the traditional Chinese medicine, thus the primary problem in the macro quality control of the traditional Chinese medicine, namely the authenticity identification of the traditional Chinese medicine is instantly solved.

Description

technical field [0001] The invention relates to a traditional Chinese medicine formula granule and its preparation method and quality control method, in particular to a Chinese yam formula granule and its preparation method and quality control method. Background technique [0002] Traditional Chinese medicine formula granules, under the guidance of the theory of traditional Chinese medicine, are made of Chinese herbal decoction pieces through various processes, and are used in clinical prescriptions of traditional Chinese medicine. Compared with traditional Chinese medicine decoction, it is convenient to take and the dosage is small , the quality is controllable, easy to store, and easy to carry; Chinese medicine formula granules are currently in the pilot production state in China, and the product technology and quality standards are not uniform. At present, traditional Chinese medicine formula granules are mostly extracted with water, or extracted with water after extracti...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61K9/16A61J3/00G01N21/35G01N21/3563
Inventor 吴玢付静张翠
Owner BEIJING KANGRENTANG PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com