Coenzyme Q10 pharmaceutical composition

A technology of composition and coenzyme, which is applied in the field of pharmaceutical compositions for injection, can solve the problems of turbid precipitation and rapid content drop, and does not solve the problem of solubility of freeze-dried preparations, so as to facilitate industrial production and reduce storage and transportation costs , good stability effect
CN101480381AInactive Publication Date: 2009-07-15郑微
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
郑微
Publication Date
2009-07-15
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a coenzyme Q10 pharmaceutical composition which mainly comprises components: (1) coenzyme Q10 is active ingredient; (2) one or multiple of polyethylene 15-oxhydryl glycol stearate (Solutol HS 15), polysorbate, PEG, poloxamer, and polyoxyethylene castor oil derived products are solubilizer; (3) one or multiple of midchain monoglyceride and derived products thereof, medium saturated or unsaturated fatty acid are oil component; and (4) injection water is solvent. One or multiple of excipient, chemical inhibitor, and osmotic pressure regulator are added for preparing injection and freeze drying agent. Compared with the traditional coenzyme Q10 pharmaceutical composition, the injection administration coenzyme Q10 pharmaceutical composition has better storage and transportation stability and higher clinical application safety and patient compliance. The injection has simple preparation process, convenient quality control, lower production cost and convenient industrial production.
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Description

technical field

[0001] The invention relates to a novel pharmaceutical composition for injection with coenzyme Q10 as an active ingredient. Background technique

[0002] Coenzyme Q10 is a fat-soluble quinone compound that widely exists in plants, microbial cells, and animal hearts, livers, spleens, and kidneys. It has a variety of biological functions, with small doses and low toxicity. The advantages of disease, widely used clinically. Coenzyme Q10 has the functions of natural anti-oxidation and activation of cell metabolism, which can significantly improve human immunity. Clinically, it is mainly used for the treatment of scurvy, aplastic anemia, duodenal ulcer, acute and chronic viral hepatitis, subacute liver necrosis, congestive heart disease, emphysema and other diseases, as well as adjuvant treatment for cancer patients.

[0003] Coenzyme Q10 is insoluble in water and easily decomposed when exposed to light, which brings many difficulties to the research of its prep...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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