Sodium alginate microballoon vein suppository containing hemangioma-resisting medicant, preparation method and application thereof

Abstract

The invention discloses a sodium alginate microballoon vein suppository containing hemangioma-resisting medicant, a preparation method and an application thereof. The sodium alginate microballoon vein suppository comprises carrier sodium alginate and hemangioma-resisting medicant; the sodium alginate covers the hemangioma-resisting medicant; the weight ratio of the sodium alginate to the hemangioma-resisting medicant is 5:1-60:1; and the hemangioma-resisting medicant is pingyangmycin, sodium morrhuate, carbamide or bleocin. The raw materials used in the invention have favorable mechanical strength, biocompatibility, biological degradability and stability, have no organic solvent, and are basically harmless to functions of hemopoietic system and immune system, thereby suppository can be industrially produced.

Description

technical field

[0001] The present invention relates to sodium alginate microsphere vascular embolism containing medicine and its preparation method and application, especially sodium alginate microsphere vascular embolism containing antiangioma drug (pingyangmycin, urea, sodium morrhuate, bleomycin) And its preparation method and application. Background technique

[0002] Hemangioma is the most common benign tumor in humans, and hemangioma of the liver is one of the most common benign tumors of the liver. It is more common in adults, and women are more common than men. Those with small tumors are asymptomatic in the early stage and are often found during physical examination. However, with the expansion of the lesion, clinically, abdominal pain, abdominal distension, hepatomegaly, abdominal mass, gastrointestinal Compression and other symptoms, and there is a risk of spontaneous and traumatic rupture and bleeding. Once the hemangioma ruptures, its hemorrhage can be fatal....