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Animal growth promoter of Chinese herbal medicine

A technology of animal growth and accelerator, applied in animal feed, animal feed, application, etc., can solve the problems of unknown active ingredients, large dosage, single dosage form, etc., and achieve the effect of promoting protein accumulation, promoting animal growth, and increasing muscle weight

Inactive Publication Date: 2012-05-09
BEIJING UNIV OF AGRI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Although people have placed great hopes on Chinese herbal medicine feed additives, and the long history has proved its effectiveness and safety. It is more difficult to meet the needs of the current international market, so it is more necessary to carry out research on dosage forms and active ingredients in the market.

Method used

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  • Animal growth promoter of Chinese herbal medicine
  • Animal growth promoter of Chinese herbal medicine
  • Animal growth promoter of Chinese herbal medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A Chinese herbal medicine animal growth promoter, which contains a component that inhibits the activity of phosphodiesterase; the component that inhibits the activity of phosphodiesterase is: Burdock fruit extract;

[0028] The extraction method of the component containing the activity of inhibiting phosphodiesterase is:

[0029] A. After soaking the Burdock Fructus crude drug in water for 30 minutes, first decoct it with strong fire to boiling, then decoct it with slow fire for 30 minutes to obtain the first decoction and place it in another container; the weight ratio of the described crude drug to water is 1 : 10;

[0030] B. Add water to the decocted burdock fruit crude drug for 30 minutes to obtain a second decoction, which is combined with the first decoction to obtain a total decoction; The weight ratio of the burdock fruit crude drug and water is 1: 10;

[0031] C. The total decoction is concentrated under reduced pressure, so that the crude drug concentration...

Embodiment 2

[0044] In this embodiment, the component containing the activity of inhibiting phosphodiesterase is: arctiin;

[0045] The arctiin was purchased from (arctin) China Institute for the Control of Pharmaceutical and Biological Products (Beijing);

[0046] The detection result of present embodiment and embodiment 1 is as follows:

[0047] Effects of the Arctium Fructus Extract and the Arctiin on mouse skeletal muscle cAMP and its phosphodiesterase activity and growth performance:

[0048] 1. Materials and methods

[0049] 1.1 Instrument

[0050] Rotary evaporator, W-O lifting constant temperature oil-water bath (Shanghai Shenshun Biotechnology Co., Ltd.), circulating water multi-purpose vacuum pump (Zhengzhou Great Wall Science, Industry and Trade Co., Ltd.), HZQ-F160 full temperature oscillating incubator (Taicang Huamei Biochemical Instrument Factory ), high performance liquid chromatography (HPLC) (Agilent 1100LC, Agilent Technologies Co., Ltd.), microplate reader (BIO-RAD, ...

Embodiment 3

[0095] Present embodiment is another technical scheme of the present invention, and the quality of raw material (component) used is identical with embodiment 1;

[0096] A Chinese herbal medicine animal growth promoter, the components containing the activity of inhibiting phosphodiesterase are reed rhizome, Cyperus cyperi, astragalus, Paulownia leaves, the weight ratio of each component in the Chinese herbal medicine animal growth promoter is:

[0097] Reed root 1-50, Rhizoma Cyperi 1-50, Astragalus 1-150, Paulownia leaf 1-500;

[0098] The unit adopted in this embodiment is gram, also can be milligram, also can be kilogram;

[0099] A preparation method of a Chinese herbal medicine animal growth promoter, the Chinese herbal medicine animal growth promoter contains a component that inhibits the activity of phosphodiesterase, and the component that contains the activity of inhibiting the phosphodiesterase is reed rhizome, Cyperus cyperi, Radix Astragali and Paulownia leaves, t...

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Abstract

The invention relates to an animal growth promoter of Chinese herbal medicine. The promoter contains a component for inhibiting the activity of phosphodiesterase, and the inhibition ratio of the activity of phosphodiesterase is larger than 20 percent. The component for inhibiting the activity of phosphodiesterase is one of great burdock achene extract and arctin; the component for inhibiting the activity of phosphodiesterase is phragmites communis, nutgrass galingale rhizome, radix astragali, paulownia leaf with the weight ratio of 1 to 50:1 to 50:1 to 150:1 to 500; and the component for inhibiting the activity of phosphodiesterase is nutgrass galingale rhizome, radix astragali, paulownia leaf and common fennel with the weight ratio of 1 to 150:1 to 200:1 to 480. The invention contains drug which can inhibit the activity of phosphodiesterase and is screened from the Chinese herbal medicine of natural product, effective combination or effective ingredients thereof, can improve endogenous cAMP of organism, further activates dependent protein kinase of cAMP, finally inhibit hydrolysis of protein, improve protein accumulation and increase muscle weight, thus promoting the animal growth.

Description

technical field [0001] The invention belongs to the field of animal feed additives, in particular to a Chinese herbal medicine animal growth promoter, which contains a component that inhibits the activity of phosphodiesterase, and the component that inhibits the activity of phosphodiesterase The inhibition rate of esterase (Phosphodiesterase, PDE for short) activity is greater than 20%. Background technique [0002] The use of feed additives to improve animal growth performance is an important means of animal husbandry. Currently available feed additives mainly include steroid hormones, β-receptor agonists, growth hormone proteolytic agents, exogenous cyclic nucleotide preparations (cAMP), natural Chinese herbal medicine feed additives, enzyme preparations, and probiotics , oligosaccharides (oligosaccharides) and organic acids, etc. Among them, the first four categories are prohibited or strictly restricted due to high cost, small application range, or safety issues. Altho...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23K1/16A23K1/14A23K10/30
Inventor 陈武谷金妮姜代勋
Owner BEIJING UNIV OF AGRI