Composite vitamin for injection and preparation method thereof

A compound vitamin and injection technology, applied in the field of injection vitamins and their preparation, can solve problems such as limitation and freeze-drying equipment damage, and achieve the effects of good stability, good stability, and small frozen crystals.
CN101632679AInactive Publication Date: 2010-01-27้‚“็››้ฝ +1

Patent Information

Authority / Receiving Office
CN ยท China
Current Assignee / Owner
้‚“็››้ฝ
Publication Date
2010-01-27
Estimated Expiration
Not applicable ยท inactive patent

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Abstract

The invention provides a composite vitamin for injection and a preparation method thereof, in particular to a composite vitamin (4) refrigerating and drying preparation for injection, which contains vitamin A palmitate, vitamin D2, vitamin E, vitamin K1, tween-80, a stabilizing agent, a proppant, and a pH regulator. Products prepared by the formulation composition and the preparation process have good appearance, fine freeze crystal, short redissolution time and good stabilization. The hemolysis test, rabbit marginal vein infusion stimulation test, systemic anaphylaxis test of the composite vitamin (4) for injection all meet the safety requirements of injecting.
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Description

Technical field:

[0001] The invention relates to a vitamin for injection and a preparation method thereof, in particular to a freeze-dried preparation of compound vitamins for injection and a preparation method thereof. technical background:

[0002] Vitamin A: It is an essential ingredient for promoting growth, maintaining the visual function of the retina, and maintaining the stability of normal cell membranes. If it is deficient, the body will stop growing, night blindness, dry eyeballs and corneal softening. Vitamin D 2 : Form bone tissue, increase the absorption of calcium and phosphorus, and osteomalacia will occur after deficiency. Vitamin E: Anti-oxidation of cell membranes, as an oxygen free radical scavenger, the lack of red blood cell destruction and hemolysis, skeletal muscle and myocardial degeneration. Vitamin K 1 : It can form prothrombin, maintain normal blood coagulation function, and cause prothrombin deficiency bleeding when lacking.

[0003] Compound ...

Claims

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