Method for the production of bridged dibenz [c,e] [1,2] - oxaphosphorin-6-oxides
A technology of phosphaphenanthrene and oxa, which is applied in the field of preparation of bridged 9-oxa-10-phosphaphenanthrene-10-oxide, which can solve the problems that are not suitable for large-scale application
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Embodiment 1
[0066] Preparation of compound VIII:
[0067]
[0068] In a vacuum-sealed glass apparatus equipped with a sturdy stirrer, thermometer, inert gas supply tube, and heating bath, 32.67 g of anhydrous 1,3,5-tris(2-hydroxyethyl)-isocyanuric acid (THIC )heating. After the THIC had melted, stirring was started and the temperature of the heating bath was lowered to 135°C. Then, 96.5 g of 10-(N(1-propyl)-amino)-9,10-dihydro-9-oxa-10-phosphaphenanthrene Ia preheated to about 120° C. were added. A few minutes after the addition of the reagent, the reactor pressure was carefully depressurized and the reaction mixture started to foam. When foaming ceased, the pressure was further slowly reduced until finally 2-5 mbar was reached. At this point, with continued agitation under the vacuum and at a temperature of 130-135°C, a homogeneous melt was gradually prepared from the two-component mixture. The 1-propylamine obtained during the conversion was condensed in a vacuum trap. use 1 H-...
Embodiment 2
[0070] Preparation of Substance IX:
[0071]
[0072] instrument:
[0073] 1 4-liter 4-neck round bottom flask equipped with the following parts:
[0074] ●Sturdy glass stirrer with vacuum-tight installation;
[0075] ●Internal thermometer;
[0076] ●Inert gas connectors;
[0077] ● Liebig condenser with condensing receiver;
[0078] ● heating bath;
[0079] ●Vacuum pump with vacuum trap.
[0080] In a 4-necked flask filled with argon or nitrogen, add 1131g (4.33mol) 1,3,5-tris(2-hydroxyethyl)-isocyanuric acid (THIC, IVa) and 1.52g p-toluenesulfonate A mixture of acid hydrates, melted and heated to 185°C with stirring. After 3 hours of reaction, the resulting water was distilled off by reducing the pressure to about 50 mbar in about 5 minutes. Next, the inert gas was supplied again and a second portion of p-toluenesulfonic acid hydrate (0.6 g) was added. The melt was then stirred for a further 8 hours at 185°C. Subsequently, the resulting water was removed at ab...
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