Chinese medicament for treating bone injury and preparation method thereof

A technology of injury and traditional Chinese medicine, applied in the field of traditional Chinese medicine for the treatment of bone injuries and its preparation, can solve the problems of tablet compressibility, friability, difficulty in controlling the difference in tablet weight, poor stability, etc., and achieve good tablet weight difference , good compressibility and strong quality controllability

Inactive Publication Date: 2010-06-16
HONGYI SCI & TECH CO LTD NANCHANG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0020] Although powders, tablets, capsules, etc. prepared from the compositions of Aconitum Aconitum, Panax notoginseng, Duanjieshen, and Baiyun ginseng have been disclosed in the prior art, the production of existing tablets is subject to conditions such as technology, technology, and equipment. The limitation of the tablet makes the compressibility, friability and tablet weight difference of the tablet difficult to control, and the stabilit

Method used

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  • Chinese medicament for treating bone injury and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Weigh 210g of Aconitum aconitum, 30g of Panax notoginseng, 15g of Duanjieginseng, 45g of Baiyun ginseng and grind them into fine powder, pass through a 100-mesh sieve, add 70g of lactose, 60g of microcrystalline cellulose, 30g of low-substituted hydroxypropyl cellulose, and polyvinylpyrrolidone K30 30g, mix evenly, add 3g of magnesium stearate, mix evenly, put it in a powder feeder for a new tablet press machine, dry powder direct tablet compression, film coating, packaging, to get ready.

[0043] Using the traditional Chinese medicine compositions and auxiliary materials of Aconitum Aconitum, Panax notoginseng, Duanjieshen, and Baiyun ginseng prepared in the proportions by weight, powders, capsules, suspensions, granules, pills, powder sprays, Spray, aerosol, tincture, suppository, ointment, cream, paste, syrup, lotion, liniment, film, paint, film, gel, patch.

Embodiment 2

[0045] Weigh 210g of Aconitum aconitum, 30g of Panax notoginseng, 15g of Duanjieginseng, and 45g of Baiyun ginseng, and grind them into fine powder, pass through a 100-mesh sieve, add 70g of mannitol, 60g of microcrystalline cellulose, 30g of cross-linked polyvinylpyrrolidone, and 30g of polyvinylpyrrolidone K30 30g, mix evenly, add 3g of magnesium stearate, mix evenly, put it in a powder feeder for a new tablet press machine, dry powder direct tablet compression, film coating, packaging, to get ready.

[0046] Using the traditional Chinese medicine compositions and auxiliary materials of Aconitum Aconitum, Panax notoginseng, Duanjieshen, and Baiyun ginseng prepared in the proportions by weight, powders, capsules, suspensions, granules, pills, powder sprays, Spray, aerosol, tincture, suppository, ointment, cream, paste, syrup, lotion, liniment, film, paint, film, gel, patch.

Embodiment 3

[0048] Weigh 210g of Aconitum aconitum, 30g of Panax notoginseng, 15g of Duanjieginseng, 45g of Baiyun ginseng and grind them into fine powder, pass through a 100-mesh sieve, add 70g of lactose, 60g of microcrystalline cellulose, 30g of low-substituted hydroxypropyl cellulose, and cross-linked carboxylate Methylcellulose sodium 30g, mixed uniformly, added magnesium stearate 3g, mixed uniformly, put in the powder feeder for new-style tablet press machine, dry powder direct tablet compression, film coating, packaging, to get final product.

[0049] Using the traditional Chinese medicine compositions and auxiliary materials of Aconitum Aconitum, Panax notoginseng, Duanjieshen, and Baiyun ginseng prepared in the proportions by weight, powders, capsules, suspensions, granules, pills, powder sprays, Spray, aerosol, tincture, suppository, ointment, cream, paste, syrup, lotion, liniment, film, paint, film, gel, patch.

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Abstract

The invention discloses tablets, which are prepared by crushing the following components into fine powder in part by weight: 100 to 300 parts of radix aconiti kusnezoffii preparata, 10 to 100 parts of sanchi, 5 to 100 parts of wallich's cynanchum root and 20 to 150 parts of crepis crocea; sieving the fine power with an 80 to 120-mesh screen; uniformly mixing the fine powder; adding a bulking agent, a disintegrating agent and a lubricating agent; uniformly mixing the mixture; placing the mixture into a powder feeder for a novel tablet machine; compressing the dry powder into tablets by a direct tablet compressing method; and coating film coats. Compared with the conventional tablet production technology, the tablets prepared from a composition of the radix aconiti kusnezoffii preparata, the sanchi, the wallich's cynanchum root and the crepis crocea has the advantages of good compressibility, breakage, and uniformity of weight, and stable quality.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating bone injuries and a preparation method thereof. Background technique [0002] Orthopedic rheumatic numbness, bruises, joint pain, etc. are common diseases, and there are few drugs to choose from clinically. [0003] 1. Aconitum: "Bie Lu" records that it governs rheumatism, her husband has kidney dampness and itching in the scrotum, cold and heat can cause lumbago, can't walk, carbuncle and pus knot; "Medicine Properties" records that it can cure aversion to wind and aversion to cold; Dong Yi Bao Jian records that it can treat rheumatism, paralysis, pain, and tetanus cold; "Compendium Supplements" records that it has the effect of chasing wind and promoting blood circulation; "Guizhou Folk Prescription Collection" records that it can treat paralysis and is an important medicine for traumatology. [0004] Aconitum kusnezoffii Reichb.: It is a processed product of the dried ...

Claims

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Application Information

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IPC IPC(8): A61K36/714A61K9/30A61K9/00A61P19/08A61P29/00A61P19/00A61P17/02
Inventor 钱进陶琳穆正义廖新华王晓霞熊水根刘孝乐
Owner HONGYI SCI & TECH CO LTD NANCHANG
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