Self-adaptive liquid level detection method for chemical lumind immunoassay analysis

Abstract

The invention provides a self-adaptive liquid level detection method for chemical lumind immunoassay analysis, which comprises the following steps of: aiming at containers at different positions, carrying out predetection on distributed capacitances in the containers by a sampling needle; setting capacitance change threshold values for the containers at the different positions; establishing matched relations for the containers at the different positions and the corresponding capacitance change threshold values; determining a current capacitance change threshold value according to the position of the sampling needle; and comparing a capacitance sensed by the sampling needle with the current capacitance change threshold value, wherein if the capacitance exceeds the range of the threshold value, a chemical lumind immunoassay analysis control system sends a control signal to control the operation of the sampling needle. The liquid level detection method has the advantages that the sampling needle can carry out self-adaptive liquid level detection according to the containers at the different positions; the accuracy is high; the error detection is effectively prevented; and safety performance and accuracy of the chemical lumind immunoassay analysis system are improved.

Description

Technical field [0001] The invention relates to the field of chemiluminescence immunoassay for medical detection, in particular to an adaptive chemiluminescence immunoassay liquid level detection method. Background technique [0002] In the field of medical testing, medical testing equipment such as fully automated biochemical analysis systems, chemiluminescence immunoassay systems, etc., use sample needles to extract samples and various reagents for biochemical reactions. The sample needles add samples and various reagents to The sample needle will cause cross-contamination of samples and reagents. In order to reduce cross-contamination, the sample needle cannot enter the sample cup or the liquid surface in the reagent cup is too deep under the drive of the stepper motor. It is necessary when the sample needle touches the liquid surface Controlling the injection needle to stop continuing to descend and start drawing samples or reagents, therefore, how to ensure that the injectio...

AI Technical Summary

Problems solved by technology

This type of device and method generates an indication signal through the change of the capacitance of the capacitance sensing probe when it touches the liquid surface, but the change of the capacitance of the probe is not only affected by the capacitance of the liquid, but also the distributed capacitance of the surrounding environment can also have an impact that cannot be ignored. Therefore, the position of the capacitive sensing probe must be fixed, and the equipment structure around the capacitive sensing probe must not change greatly. Based on this limitation, the reagent cups and sample cups in the existing automatic biochemical analyzers are arranged in a disc arrangement. , the aspirating probe is set at a fixed position for aspirating action. However, for the non-disc type chemiluminescence immunoassay system, since the sampling needle needs to aspirate samples and various reagents at different positions of the equipment, and then add them to the When the cuvette reacts, the distributed capacitance around the sampling needle will also change greatly. When the change of the distributed capacitance exceeds the preset threshold, the sampling needle will output an incorrect liquid level indication signal, which in turn will cause the control system to issue a warning signal to the sampling needle. Wrong action signal, wrong suction and leakage, and even damage to the sampling needle and other parts of the equipment

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