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Progesterone composite preparation for regulating and controlling estrus of cow

A technology of compound preparations and cows, applied in the direction of medical preparations containing active ingredients, drug combinations, organic active ingredients, etc., can solve problems such as poor ovulation during the same period

Inactive Publication Date: 2010-10-13
GUAZHOU LONGXING ANIMAL HUSBANDRY IND DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this method has poor estrus and ovulation synchronization.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] For adult cows, the dose is 4 ml per head, and the compound preparation is prepared:

[0021] 1. Drug weighing

[0022] Weigh 60 mg of progesterone and 3.25 mg of estradiol with an analytical balance, and crush them respectively.

[0023] 2. Take 0.25ml of sterilized edible vegetable oil, heat it to 250°C in a glass dish and keep it for 20 minutes, then cool it to 50°C, add crushed progesterone and estradiol powder respectively, stir and dissolve; pour the dissolved liquid medicine Put it into another container, continue to heat the undissolved medicinal solution to 80°C, and let it stand for 30 minutes; mix the twice dissolved medicinal solution evenly.

[0024] 3. Seal the mixed liquid medicine into 50ml, 100ml, 200ml glass bottles respectively, and label them for use.

Embodiment 2

[0026] For young cows, administer 4 ml of the total amount per head, and the preparation of the compound preparation:

[0027] 1. Drug weighing

[0028] Weigh 70 mg of progesterone and 4 mg of estradiol with an analytical balance, and crush them respectively.

[0029] 2. Take 0.25ml of sterilized edible vegetable oil, heat it to 250°C in a glass dish and keep it for 20 minutes, then cool it to 50°C, add crushed progesterone and estradiol powder respectively, stir and dissolve; pour the dissolved liquid medicine Put it into another container, continue to heat the undissolved medicinal solution to 70°C, and let it stand for 30 minutes; mix the twice dissolved medicinal solution evenly.

[0030] c. Seal the mixed medicinal solution into 50ml, 100ml, 200ml glass bottles respectively, and label them for use.

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Abstract

The invention discloses a progesterone composite preparation for regulating and controlling estrus of a cow. The progesterone composite preparation is prepared by the following steps of: dissolving progesterone with edible vegetable oil to prepare solution, every milliliter of which contains 20mg of progesterone; dissolving estradiol with sterilized edible vegetable oil to prepare the solution, every milliliter of which contains 10mg of estradiol; and preparing the progesterone composite preparation from 75.00 to 87.50 weight percent of the solution of the progesterone, 8.75 to 10.00 weight percent of the solution of the estradiol and 2.50 to 6.25 weight percent of the edible vegetable oil. The progesterone composite preparation comprises estrogen and progesterone, is injected for regulating and controlling the estrus of the cow, and can obviously improve the estrus synchronization rate and the estrus conception rate of the cow. When used for pre-processing, the progesterone composite preparation can improve the activity of the ovary of the processed cow and the sensitivity to gonadotropic hormone so as to stimulate estrogen secretion and promote follicular development and can prevent insufficient secretion of the progesterone of the processed cow so as not to affect the sexual desire and the estrus of the cow.

Description

technical field [0001] The invention relates to a hormone preparation injected during estrus regulation and treatment of cows, which contains estrogen and progesterone, in particular to a progesterone compound preparation for cow estrus regulation and control. Background technique [0002] Cow estrus control technology began in the late 1940s. Christain (1948) injected progesterone into group cows to make them estrus cycle, in order to improve the efficiency of artificial insemination, and implement livestock breed improvement at the same time. Over the past half century, people's understanding of the process of maternal reproduction has greatly improved. The establishment of radioimmunoassay technology has enabled people to have a deep understanding of the regulation of reproduction by reproductive hormones, and hormone preparations continue to emerge. With the intensive and large-scale development of animal husbandry and the popularization of artificial insemination tech...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/57A61K31/565A61P15/08
Inventor 张居农
Owner GUAZHOU LONGXING ANIMAL HUSBANDRY IND DEV
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