The invention provides a method for controlling estrus synchronization of maria by adopting traditional Chinese medicines. A medicine composition comprises the following raw medicines: Chinese angelica, motherwort herb, prepared rhizome of rehmannia, dried tangerine peel, white peony root, Chinese yam and dwarf lilyturf tuber. The medicine composition has the beneficial effects that the medicine composition takes warming the spleen and stomach for dispelling cold and benefiting qi and raising Yang as the treatment principles, is reasonable in composition, has simple preparation processes and has a wide range of application; the medicine composition is prepared from pure Chinese herbal medicines, has a wide source, is low in cost, has a high cure rate and does not have residues or toxic or side effect; in particular, plant cell walls are furthest destroyed after superfine grinding, thus overcoming the defects that traditional medicine powder has high content of crude fibers and active ingredients are hard to dissolve out and being easier to absorb by horses; the medicine composition has obvious functions of activating blood and adjusting body functions, effectively controls estrus synchronization of maria, has smaller toxic and side effects than western medicines, and does not have medicine residues.