Xanthan-gum-containing pharmaceutical preparation for joint intracavity injection

A pharmaceutical preparation, the technology of xanthan gum, applied in the field of medicine, can solve the problems of long treatment course and slow repair speed, and achieve the effect of relieving patients' pain, good lubrication and protection, and conducive to sports penetration

Active Publication Date: 2012-07-18
INST OF BIOPHARM OF SHANDONG PROVINCE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, although sodium hyaluronate alone can repair the damaged cartilage and treat osteoarthritis fundamentally, the repair speed is slow and the required course of treatment is long.

Method used

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  • Xanthan-gum-containing pharmaceutical preparation for joint intracavity injection
  • Xanthan-gum-containing pharmaceutical preparation for joint intracavity injection
  • Xanthan-gum-containing pharmaceutical preparation for joint intracavity injection

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Example 1: A liquid preparation for intra-articular injection

[0014] Party:

[0015]

Embodiment 2

[0016] Example 2: A gel formulation for intra-articular injection

[0017] Party:

[0018]

Embodiment 3

[0019] Example 3: A gel formulation for intra-articular injection

[0020] Party:

[0021]

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Abstract

The invention provides a xanthan-gum-containing pharmaceutical preparation for joint intracavity injection, which is characterized by containing xanthan gum. In the preparation, xanthan gum used as a pharmaceutical component for joint cavity injection has the advantages of favorable viscoelasticity and favorable lubricating property, has particular thixotropy, can be used as an excellent pharmaceutical release-control carrier, and can act in the joint cavity for a long time. The pharmaceutical preparation can improve and treat rheumatism, rheumatoid arthritis, osteoarthritis, synovitis and / orcartilage injury, and effectively relieve pain of patients.

Description

Technical field [0001] The invention belongs to the technical field of medicine and provides a pharmaceutical preparation for intra-articular injection containing xanthan gum. Background technique [0002] Osteoarthritis, also known as osteoarthritis, degenerative arthritis, proliferative arthritis, senile arthritis and hypertrophic arthritis, etc., occur in the knee joints, hip joints, spine and In finger joints and other parts, the articular cartilage has undergone degeneration, and bone spurs are formed on the edges of the joints. Osteoarthritis is more common in the elderly. As the average life span of human beings increases, the incidence of osteoarthritis is getting higher and higher. It seriously hinders work and becomes one of the most common reasons for the loss of labor after the age of 50. As a result, bones and joints Inflammation has become a major problem to be solved urgently. [0003] The pathogenesis of osteoarthritis is not well understood. Its occurrence and d...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/723A61K31/728A61K31/737A61K31/734A61K31/732A61K31/736A61K31/729A61P19/02A61P19/04A61K31/722A61K31/717A61K31/685
Inventor 凌沛学朱希强郭学平李海军颜震韩冠英
Owner INST OF BIOPHARM OF SHANDONG PROVINCE
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