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Lacrimal implants and related methods

A technology of lacrimal implants and implant bodies, which is applied in the field of eye implants and can solve the problems of liquid droplets missing the eyes

Active Publication Date: 2011-04-13
MATI THERAPEUTICS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, one or more droplets may miss the eye

Method used

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  • Lacrimal implants and related methods

Examples

Experimental program
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experiment Embodiment 1

[0255] Figure 12 A lacrimal implant 1200 is illustrated that includes an implant body that includes a retention structure. In this example, the retention structure wraps around the Oasis hydrogel retention element. In order for the Oasis hydrogel retention element to receive fluid, the retention structure includes a fluid permeable retainer in the form of a silicone / contact lens hydrophilic cap component. In this example, the cap component comprised 80% silicone and 20% contact lens material (Vista Optics 75). In addition to allowing fluid to be received into the retention structure, the silicone / contact lens cap component additionally inhibits the Oasis hydrogel from sticking out of the retention structure during swelling.

[0256] At 1202, the Oasis hydrogel and package retention structure at t=0 minutes are shown. At 1203, the Oasis hydrogel and package retention structure at t=5 minutes are shown. At 1204, the Oasis hydrogel and package retention structure at t=10 min...

experiment Embodiment 2

[0258] Figure 13 A lacrimal implant 1300 is illustrated that includes an implant body that includes a retention structure. In this example, the retention structure encapsulates the TG-2000 hydrogel retention element. In order for the TG-2000 hydrogel retention element to receive fluid, the retention structure includes a fluid permeable retainer in the form of a silicone / contact lens hydrophilic cap component. In this example, the cap component comprised 80% silicone and 20% contact lens material (Vista Optics 75). In addition to allowing fluid to be received into the retention structure, the silicone / contact lens cap component additionally inhibits the TG-2000 hydrogel from sticking out of the retention structure during swelling.

[0259] At 1302, the TG-2000 hydrogel and encapsulated retention structures at t=0 minutes are shown. At 1304, the TG-2000 hydrogel and encapsulated retention structures at t=5 minutes are shown. At 1306, the TG-2000 hydrogel and encapsulated re...

experiment Embodiment 3

[0261] Figure 14 A lacrimal implant 1400 is illustrated that includes an implant body that includes a retention structure. In this example, the retention structure wraps the Contamac-78% hydrogel retention element. In order for the Contamac-78% hydrogel retention element to receive fluid, the retention structure includes a fluid permeable retainer in the form of a silicone / contact lens hydrophilic cap component. In this example, the cap component comprised 80% silicone and 20% contact lens material (Vista Optics 75). In addition to allowing fluid to be received into the retention structure, the silicone / contact lens cap component additionally inhibits the Contamac-78% hydrogel from sticking out of the retention structure during swelling.

[0262] At 1402, the Contamac-78% hydrogel at t=0 minutes and the encapsulated retention structure are shown. At 1404, the Contamac-78% hydrogel at t=5 minutes and the encapsulated retention structure are shown. At 1406, the Contamac-78%...

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Abstract

Lacrimal implants and related methods providing secure retention within the lacrimal punctum of an eye are described. The lacrimal implants can comprise a implant body configured for at least partial insertion through the lacrimal punctum and into a lacrimal canaliculus. The implant body can include a deformable retention structure that can be configured to substantially encapsulate an expandable retention element. In some examples, the expandable retention element can include a fluid absorbing material, which can be exposed to fluid such as via a fluid permeable retainer or a fluid permeable aperture. As the fluid absorbing material retains fluid (i.e., upon acceptance of fluid into the retention structure), its size increases and its shape can change to urge one or more portions of the retention structure outward, such as against a wall of the lacrimal canaliculus, thereby securely retaining the lacrimal implant within the punctum.

Description

[0001] priority statement [0002] This application claims the benefit of priority to U.S. Provisional Patent Application Serial No. 61 / 066,233, filed February 18, 2008, and U.S. Provisional Patent Application Serial No. 61 / 049,347, filed April 30, 2008, the specifications of which are incorporated by reference This reference is incorporated herein in its entirety. technical field [0003] This patent document generally relates to ocular implants. More specifically, but not in a limiting manner, this patent document relates to lacrimal implants (e.g., canaliculus plugs), methods of making these implants, and the use of these implants for the treatment of ocular diseases ( ocular disease) method. Background technique [0004] In the field of eye disease treatment, patients and physicians face a variety of challenges, including the delivery of drugs to the eye and the treatment of dry eye. Dry eye, including keratoconjunctivitis sicca, is a common ocular condition requiring...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F9/007
CPCA61F2210/0061A61F9/00772A61P27/02A61F9/00781A61F9/0017A61M31/002A61K9/0051A61M29/02A61M31/00A61B17/12022A61M2210/0612A61M2207/00
Inventor R·贾因R·W·施密祖
Owner MATI THERAPEUTICS
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