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Perfusate and preparation method thereof for treating cow recessive mastitis

A technique for perfusion fluid and mastitis, applied in the field of medicine, can solve the problems of reducing the curative effect and increasing the residue of antibiotics, etc., and achieve the effects of exact curative effect, high drug concentration and strong pertinence

Inactive Publication Date: 2011-05-25
河南亚卫动物药业有限公司
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  • Abstract
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Problems solved by technology

However, long-term repeated use of antibiotics for western medicine treatment can easily make pathogens resistant to the drugs, thereby reducing the curative effect and increasing the residue of antibiotics in milk

Method used

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  • Perfusate and preparation method thereof for treating cow recessive mastitis
  • Perfusate and preparation method thereof for treating cow recessive mastitis
  • Perfusate and preparation method thereof for treating cow recessive mastitis

Examples

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Embodiment 1-5

[0011] Example 1-5: A perfusion solution for the treatment of invisible mastitis in dairy cows. The ratio of raw materials contained in the perfusion solution is shown in Table 1.

[0012]

[0013] The preparation method of the perfusate is described in detail in Example 1:

[0014] ①Add 9 times the weight of the two in 4000g of astragalus and 5000g of epimedium, decoct 2 times, the first 2h, the second 1h, combine the decoction, filter, and concentrate the filtrate to a density of 1.25g / cm 3 , Then add absolute ethanol until the ethanol concentration accounts for 70% of the total volume of the solution, stand still and filter, and recover the ethanol in the filtrate to obtain solution a;

[0015] ②Add 300g levamisole hydrochloride and 375g antimicrobial peptide to 2500ml water for injection, stir and dissolve to obtain solution b;

[0016] ③Add 2500ml glycerin to 2500ml water for injection, add 400g gelatin when heated to 70℃, stir to dissolve to obtain solution c; then mix solu...

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Abstract

The invention relates to perfusate for treating cow recessive mastitis, which mainly comprises the raw materials with the following ratios: 4000-5000g of radix astragali, 4000-5000g of herba epimedii, 300-500g of levamisole hydrochloride, 300-400g of antibacterial pepetide, 2000-3000ml of glycerol, 400-500g of gelatine, and 50-100g of sodium benzoate, wherein pH of the perfusate is 5.5-7.5. The perfusate is used for treating cow recessive mastitis with determine curative effect, drug concentration for local application is high, absorption ratio is high, the direction is high, drug application is convenient and safe, thereby the goal of fast treating cow recessive mastitis is achieved, and the perfusate is compound perfusion preparation combining antibiosis, antiphlogosis and improving immunity of the organism.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a perfusate for treating invisible mastitis in cows and a preparation method thereof. Background technique [0002] Invisible mastitis is one of the most common diseases of dairy cows. Its udder inflammation without clinical symptoms, that is, there are no visible changes in the udder and milk of sick cows, is also called subclinical mastitis. Since there is no abnormality in the breast and milk, it is often ignored by the breeders, but the physical and chemical properties of the milk, such as conductivity, somatic cell count, and pH value, have undergone substantial changes, which must be detected by special physical and chemical methods, such as through the detection of pathogenic bacteria or body Cell testing is diagnostic. The incidence of invisible mastitis is high, which is 15 to 40 times that of clinical mastitis. When it is severe, it can develop into clinic...

Claims

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Application Information

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IPC IPC(8): A61K38/00A61P15/14A61K31/429A61K36/481
Inventor 李明魁唐洪峰闫树森张遂平郭芳茹牛永梅
Owner 河南亚卫动物药业有限公司
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