Device and method for optical parallel analysis of a sample arrangement and corresponding manufacturing method
An optical device and sample technology, which can be used in material analysis by optical means, chemical instruments and methods, measurement devices, etc. Effect
Inactive Publication Date: 2011-09-21
ROBERT BOSCH GMBH
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- Abstract
- Description
- Claims
- Application Information
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Problems solved by technology
In this regard, the light beam ST is a disturbing beam and reduces the signal-to-noise ratio of the sample area K1
Method used
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[0027] In the drawings, the same reference numerals denote the same or functionally equivalent elements.
[0028] figure 1 is a schematic diagram of a device for optically parallel analysis of sample arrangements in the form of a microtiter plate according to a first embodiment of the present invention.
[0029] exist figure 1 , the reference numeral 1 denotes a carrier substrate in the form of a microtiter plate, which is made of plastic. as reference Figure 4 Like the described microtiter plate, the carrier substrate 1 has cavities K1 , K2 as sample regions for receiving the sample substances A1 , A2 . The sample regions K1 , K2 etc. are usually arranged in matrix form on the rectangular carrier substrate 1 . The carrier substrate 1 has a thickness H between 2-4 mm P . The thickness of the sample area K1, K2 is H W Indicated and usually 0.6-0.8mm.
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The invention relates to a device and a method for optical parallel analysis of a sample arrangement and corresponding manufacturing method. The device includes a system of sample areas provided on and / or in a front face of the carrier substrate for receiving a sample substance; a system of detector areas provided on and / or in a back face of the carrier substrate, each detector area being assigned to a corresponding sample area; and a system of optical devices, each optical system being assigned to a corresponding sample area and being designed in such a way that it deflects light beams, which the corresponding sample area in response to an optical excitation does not emit in the direction of a detector area assigned to it, in the direction of the detector area assigned to it and / or in the direction of a detector-free area on the back face of the carrier substrate.
Description
technical field [0001] The present invention relates to an apparatus and method for optically parallel analysis of sample arrangements and a corresponding method of manufacture. Background technique [0002] Although any device can be used for optically parallel analysis of the sample arrangement, the invention and the problems on which it is based are explained with regard to use on a microtiter plate. [0003] In order to optically study individual samples of biochemistry, microtiter plates or DNA chips are often used, in which the study objects are arranged in discrete sample areas spatially separated from each other. By performing optical analysis on a large number of individual samples in parallel, results are obtained faster than if the individual analyses were performed sequentially. Reagents are additionally saved by miniaturizing individual formulations. [0004] Microtiter plates are generally rectangular and contain a plurality of small dishes in isolated rows a...
Claims
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Patent Timeline
Login to View More IPC IPC(8): G01N21/63G01N21/03G01N33/483
CPCB01L2300/0654G01N21/0303G01N2201/064B01L3/5085B01L2200/026G01N21/645G01N2021/6482B01L2200/141G01N2021/6463Y10T29/49908Y10T29/4998
Inventor M.多布J.鲁普
Owner ROBERT BOSCH GMBH