Method for preparing sodium quercetin-7-sulfate and application of sodium quercetin-7-sulfate to preparation of medicaments and health-care products for resisting thrombus

A technology of sulfate sodium salt and antithrombotic drug, which is applied in the application field of preparing antithrombotic drugs and health care products, and can solve problems such as undiscovered SQMS and the like
CN102247352AInactive Publication Date: 2011-11-23GUANGDONG MEDICAL UNIV
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Patent Information

Authority / Receiving Office
CN ยท China
Current Assignee / Owner
GUANGDONG MEDICAL UNIV
Publication Date
2011-11-23
Estimated Expiration
Not applicable ยท inactive patent

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Abstract

The invention belongs to a method for preparing sodium quercetin-7-sulfate and application of the sodium quercetin-7-sulfate to the preparation of medicaments and health-care products for resisting thrombus. The sodium quercetin-7-sulfate is applied to the preparation of medicaments and health-care products for resisting platelet aggregation and the thrombus or is used as components of the medicaments and the health-care products for resisting the platelet aggregation and the thrombus or is used as the precursor of the medicaments for resisting the platelet aggregation and the thrombus to be transformed. The sodium quercetin-7-sulfate which is subjected to artificial semisynthesis can inhibit the platelet aggregation obviously and prevent thrombopoiesis, and has good effects of resisting the platelet aggregation and the thrombopoiesis.
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Description

Technical field

[0001] The invention belongs to a preparation method of quercetin-7-sulfate sodium salt and its application in preparing antithrombotic drugs and health products. Background technique

[0002] Thrombotic disease is a common disease, often manifested as myocardial infarction, ischemic cerebral infarction and venous thrombosis. The investigation found that thrombotic diseases are the leading cause of death in the elderly and seriously threaten human health. At present, three types of anticoagulants, antiplatelet aggregation drugs and fibrinolytic drugs are mainly used clinically to prevent and treat thromboembolic diseases. Antiplatelet drugs have the function of inhibiting the adhesion, aggregation and release of platelets, thereby preventing thrombosis. Antiplatelet drugs can effectively prevent the occurrence of cardiovascular disease and prolong the survival period of patients. Antiplatelet drugs are increasingly used in clinical practice. However, the long-t...

Claims

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