Medical adhesive or hemostatic
A technology of hemostatic agent and adhesive, which is applied in the field of medical adhesive or hemostatic agent, can solve the problems of toxicity, etc., and achieve the effect of low cost, low price, and simple preparation process
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Embodiment 1
[0029] Weigh 10g of gelatin and dissolve it in 100ml of water, add 1g of EDC, add 3g of ethylenediamine, stir and react at 37°C for 5 hours. The reaction solution was put into a dialysis bag and dialyzed against deionized water for 2 days. After dialysis, the aqueous solution was frozen in a -80°C refrigerator, and then frozen at -53°C to obtain aminated gelatin.
Embodiment 2
[0031] Take 10 g of glucose and add it into 100 ml of deionized water to prepare a 10% dextran solution. Get 10g NaIO4 (sodium periodate) and dissolve in 100ml deionized water to prepare 10% NaIO4 solution. Then the two solutions were mixed and stirred at room temperature for 5 h. The product was put into a dialysis bag and dialyzed for two days, and the dialyzed aqueous solution was frozen in a refrigerator at -80°C, and then freeze-dried to obtain aldylated dextran.
Embodiment 3
[0033] Take 10 g of hydroxyethyl starch and add it into 100 ml of deionized water to prepare a 10% aqueous solution of hydroxyethyl starch. Get 10gNaIO4 Dissolve in 100ml deionized water to prepare a 10% NaIO4 solution. The two solutions were then mixed and reacted with stirring at room temperature for 5 hours. The product was put into a dialysis bag and dialyzed for two days, and the dialyzed aqueous solution was frozen in a refrigerator at -80°C, and then freeze-dried to obtain formylated hydroxyethyl starch.
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