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Hepatic fibrosis detection equipment and system

A technology for liver fibrosis and detection equipment, applied in the field of liver fibrosis research, can solve the problems of affecting the results, high cost, limitation of imaging methods, etc., and achieve the effect of accurate results

Active Publication Date: 2012-01-04
INNER MONGOLIA FURUI MEDICAL SCI
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Problems solved by technology

[0003] However, the gold standard liver biopsy is an invasive diagnostic method, which requires a long time for patients to recover, has safety problems, and sample deviation affects the results; the existing biochemical models of serum markers have low accuracy, sensitivity, or high cost. The reason is that it has not been widely used in clinical practice; the imaging method is limited by the equipment; the hardness value measured by FS is not only used as a detection of liver fibrosis, but also has a certain relationship with the corresponding liver function and lesions. Although Fibroscan has been widely used, due to its limitations , some patients could not detect

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  • Hepatic fibrosis detection equipment and system

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Embodiment Construction

[0028] The present invention will be described more fully hereinafter with reference to the accompanying drawings, in which exemplary embodiments of the invention are illustrated. In the drawings, the same reference numerals denote the same or similar components or elements.

[0029] In this paper, the vector is a set of various indicators provided by a patient, and the model f is a mapping function: x→{0, 1, 2, ..., n}, n takes the value of 3, 4, or other integers for example . That is, given a patient index vector x, the model predicts that the patient's pathological stage of liver fibrosis is f(x), and the value of f(x) is a set of {0, 1, 2, ..., n} n types One of the discrete values. Specific indicators and classification models are important contents of this technology. The indicators and classification models used in this patent will be introduced below.

[0030] figure 1 A structural diagram of the first embodiment of the liver fibrosis detection device according t...

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Abstract

The invention discloses hepatic fibrosis detection system, relating to the technical field of hepatic fibrosis research. The hepatic fibrosis detection system comprises a transient elastography device an input device, a classifier and an output device, wherein the input device is used for receiving ages and serum biochemical indicators, and the serum biochemical indicators at least comprise blood platelet, hyaluronic acid (HA), serum direct bilirubin (DBIL), prothrombin time (PT), alanine aminotransferase / serum glutamic pyruvic transaminase (ALT; GPT), and aspartate transaminase / serum glutamic oxalacetic transaminase (AST; GOT); the classifier is used for performing hepatic fibrosis staging according to the ages and the serum biochemical indicators and received by the input device and transient elasticity imaging data; and the output device is used for outputting of hepatic fibrosis staging results of the classifier. The hepatic fibrosis detection system of the embodiment disclosed by the invention has the advantages of noninvasiveness, strong practicability, simple and convenient method, low price, good safety and the like.

Description

technical field [0001] The invention relates to the technical field of liver fibrosis research, in particular to a liver fibrosis detection device and system. Background technique [0002] Currently, the diagnostic methods of liver fibrosis and cirrhosis clinically used are generally as follows: (1) gold standard liver biopsy, that is, pathological reading of liver tissue biopsy, and staging of liver fibrosis; There are 5 stages of S0, S1, S2, S3, and S4 (Chinese hepatitis B pathological scoring standard), and hepatitis C, for example, is divided into 5 stages of F0, F1, F2, F3, and F4 (Metavir scoring); this method is an invasive diagnostic method; (2) Serum detection, currently there are more than a dozen diagnostic models for simulating serological indicators. These models use mathematical calculations (such as statistical regression methods) to obtain mathematical formulas based on the combination of different serum biochemical indicators; (3) Imaging Detection, such as...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00
Inventor 王冠一杨勇
Owner INNER MONGOLIA FURUI MEDICAL SCI
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