Metal support and manufacturing method thereof

Abstract

The invention discloses a metal support and a manufacturing method thereof. The metal support comprises a support body, wherein a plurality of holes are distributed on the peripheral surface of the support body; and the inner surface of the support body is a smooth surface. When the metal support is used as a medicine eluting support, the holes of the metal support are loaded with a medicine and a polymeric coating is not required to load the medicine, so that the problem caused by use of polymer can be avoided; and the holes are only distributed on the peripheral surface of the support body, so that the releasing direction of the medicine can be controlled and the utilization rate of the medicine can be improved.

Description

technical field [0001] The present application relates to the technical field of medical devices, in particular to a metal stent for a drug-eluting stent and a preparation method thereof. Background technique [0002] In recent years, drug-eluting stents (drug-eluting stent, DES) have been widely used clinically. Drug-eluting stents, also known as drug-releasing stents, carry drugs through polymers coated on the surface of the metal stent or through holes on the surface of the metal stent. Compared with bare metal stents, after implantation in the human body, drug-eluting stents can continuously release drugs to the diseased tissues in contact with them, thereby effectively inhibiting the proliferation of smooth muscle on the inner wall of blood vessels and reducing the occurrence of restenosis in stents. [0003] However, through the study of the prior art, the applicant found that the existing metal stents have the following problems when they are used for drug-eluting st...

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Problems solved by technology

[0003] However, through the study of the prior art, the applicant found that the existing metal stents have the following problems when they are used for drug-eluting stents: 1. The use of polymers to carry drugs, after long-term implantation in the human body, due to the long-term durability of the polymers on its surface Presence or degradation of the polymer leads to a persistent inflammatory response that may lead to delayed endothelialization and late vascular restenosis catch-up

2. Use the holes on the surface of the metal stent to carry drugs. Since the surface of the metal stent is provided with micropores, the inner and outer surfaces and even the sides of the drug-eluting stent will be coated with drugs, so after implanting in the human body, it will cause The concentration of the drug in the blood vessel is relatively high, and the release direction cannot be effectively controlled, so that part of the drug cannot be absorbed by the blood vessel wall, and the effective utilization rate of the drug is low

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